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IL21 Receptor is a novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
![Bioactivity IL-21R [Unconjugated]](http://images.novusbio.com/fullsize2/9249-r2_recombinant-human-il-21-r-his-tag-protein-cf-bioactivity-131020201188.jpg)
![Bioactivity IL-21R [Unconjugated]](http://images.novusbio.com/fullsize/protein/991-r2_recombinant-human-il-21-r-fc-chimera-protein-cf-bioactivity-13102020115444.jpg)