IL-2 Antibody (5334) [Unconjugated]


IL‑2 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) treated with calcium ionomycin and PMA using Mouse Anti-Human IL‑2 Monoclonal Antibody (Catalog # MAB202) at 8 µg/mL for more
Recombinant Human IL‑2 (Catalog # 202-IL) stimulates proliferation in the CTLL‑2 mouse cytotoxic T cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL‑2 (2 ng/mL) is more

Product Details

Reactivity HuSpecies Glossary
Applications B/N, CyTOF-ready, Flow, ICC/IF

IL-2 Antibody (5334) [Unconjugated] Summary

E. coli-derived recombinant human IL‑2
Accession # NP_000577
Detects human IL-2 in direct ELISAs. Does not cross-react with recombinant IL-2 from mouse, rat, pig, or cotton rat.
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • CyTOF-ready
  • Immunocytochemistry 8-25 ug/mL
  • Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells
  • Neutralization 0.015-0.03 ug/mL
Read Publications using
MAB202 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL-2 Antibody (5334) [Unconjugated]

  • aldesleukin
  • IL2
  • IL-2
  • IL-2lymphokine
  • interleukin 2
  • interleukin-2
  • involved in regulation of T-cell clonal expansion
  • T cell growth factor
  • T-cell growth factor
  • TCGF


Interleukin 2 (IL-2) is a cytokine that stimulates the growth and differentiation of B cells, T cells, NK cells, and monocyte/macrophages. It functions through the heterotrimeric IL-2 receptor comprising alpha, beta, and gamma chains.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Mu, Rt
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Species: Hu
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Species: Hu, Mu
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Species: Hu
Applications: WB, AgAct
Species: Hu
Applications: WB, ELISA, ICC/IF
Species: Hu
Applications: WB, ICC/IF
Species: Hu
Applications: B/N, CyTOF-ready, Flow, ICC/IF

Publications for IL-2 Antibody (MAB202)(12)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: Bioassay, Flow, Neut.

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Showing Publications 1 - 10 of 12. Show All 12 Publications.
Publications using MAB202 Applications Species
T Carmenate, Y Ortíz, M Enamorado, K García-Mar, J Avellanet, E Moreno, L Graça, K León Blocking IL-2 Signal In Vivo with an IL-2 Antagonist Reduces Tumor Growth through the Control of Regulatory T Cells J. Immunol., 2018;0(0):. 2018 [PMID: 29618524] (Bioassay, Human) Bioassay Human
S Revu, J Wu, M Henkel, N Rittenhous, A Menk, GM Delgoffe, AC Poholek, MJ McGeachy IL-23 and IL-1? Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation Cell Rep, 2018;22(10):2642-2653. 2018 [PMID: 29514093] (Neut,, Human) Neut Human
Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling Sci Rep, 2016;6(0):32320. 2016 [PMID: 27586092] (Flow,, Human) Flow Human
Activin A programs the differentiation of human TFH cells Nat Immunol, 2016;17(8):976-84. 2016 [PMID: 27376469] (Bioassay,, Human) Bioassay Human
Nata T, Basheer A, Cocchi F, van Besien R, Massoud R, Jacobson S, Azimi N, Tagaya Y Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum. J Biol Chem, 2015;290(37):22338-51. 2015 [PMID: 26183780] (Neut,, Human) Neut Human
Kim, Dae Won, Zloza, Andrew, Broucek, Joseph, Schenkel, Jason M, Ruby, Carl, Samaha, Georges, Kaufman, Howard L Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells. J Transl Med, 2014;12(0):113. 2014 [PMID: 24885155] (Neut,, Human) Neut Human
ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation. Blood, 2012;119(26):6268-77. 2012 [PMID: 22577174] (Neut,, Human) Neut Human
Hutnick NA, Carnathan D, Demers K, Makedonas G, Ertl HC, Betts MR Adenovirus-specific human T cells are pervasive, polyfunctional, and cross-reactive. Vaccine, 2010;28(8):1932-41. 2010 [PMID: 20188249] (Flow,, Human) Flow Human
Withers DR, Fiorini C, Fischer RT, Ettinger R, Lipsky PE, Grammer AC T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue. Blood, 2007;109(11):4856-64. 2007 [PMID: 17299094] (Neut,, Human) Neut Human
Karenko L, Hahtola S, Paivinen S, Karhu R, Syrja S, Kahkonen M, Nedoszytko B, Kytölä S, Zhou Y, Blazevic V, Pesonen M, Nevala H, Nupponen N, Sihto H, Krebs I, Poustka A, Roszkiewicz J, Saksela K, Peterson P, Visakorpi T, Ranki A Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue. Cancer Res., 2005;65(18):8101-10. 2005 [PMID: 16166283] (Flow,, Human) Flow Human
Show All 12 Publications.

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Gene Symbol IL2