IL-17F Antibody (4H1629) Summary
Full-length recombinant MRkIPkVGHT FFQkPESCPP VPGGSMkLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGkEDISMN SVPIQQETLV VRRkHQGCSV SFQLEkVLVT VGCTCVTPVI HHVQ
Protein G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 0.5-2ug/ml~
- Immunohistochemistry 5 ug/ml
- Immunohistochemistry-Paraffin 5 ug/ml
Note: The human IL17F protein shows 60% sequence similarity with Rat and 57% with Mouse, and in our testing this antibody did not react with Rat or Mouse recombinant IL17F proteins.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1 ml PBS
0.05% Sodium Azide
Protein G purified
Alternate Names for IL-17F Antibody (4H1629)
- Cytokine ML-1
- interleukin 17F
Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by a subset of T helper cells that develops distinct from the Th1- and Th2- cell differentiation pathways. IL-17, also known as CTLA-8, stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis. TGF-Beta (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines. IL-17 (~32kDa) protein is produced and exists as a homo-dimer, has homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterzed and highly expressed by activated effector memory T cells.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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