IL-17F Antibody (4H1629)

Images

 
Western Blot: IL-17F Antibody (4H1629) [NBP2-27327] - Analysis on full-length recombinant IL-17F proteins of (1) Human, (2) Mouse and (3) Rat using IL-17F antibody (clone 4H1629) at a concentration of 0.5 ug/ml. Note: ...read more
Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629) [NBP2-27327] - Detection IL-17F protein in a tissue section of human lymph node cancer using IL-17F antibody (clone 4H1629) at a concentration of 5 ug/ml.
Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629) [NBP2-27327] - Analysis of IL-17F in formalin-fixed paraffin-embedded human colon tissue using an isotype control (top left) and IL-17F antibody (bottom left and ...read more
Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629) [NBP2-27327] - Detection -IL-17F protein in a tissue section of normal human stomach using IL-17F antibody (clone 4H1629) at a concentration of 5 ug/ml. ...read more
Immunohistochemistry-Paraffin: IL-17F Antibody (4H1629) [NBP2-27327] - Detection IL17F protein in a tissue section of human stomach cancer using IL17F antibody (clone 4H1629) at a concentration of 5 ug/ml. Diffused ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clone
4H1629
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

IL-17F Antibody (4H1629) Summary

Immunogen
Full-length recombinant MRkIPkVGHT FFQkPESCPP VPGGSMkLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGkEDISMN SVPIQQETLV VRRkHQGCSV SFQLEkVLVT VGCTCVTPVI HHVQ
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IL17F
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5-2ug/ml~
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml

Reactivity Notes

Note: The human IL17F protein shows 60% sequence similarity with Rat and 57% with Mouse, and in our testing this antibody did not react with Rat or Mouse recombinant IL17F proteins.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.1 ml PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for IL-17F Antibody (4H1629)

  • Cytokine ML-1
  • IL17F
  • IL-17F
  • IL-17Finterleukin-17F
  • IL24
  • IL-24
  • interleukin 17F
  • Interleukin-24
  • ML-1
  • ML1interleukin-24

Background

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by a subset of T helper cells that develops distinct from the Th1- and Th2- cell differentiation pathways. IL-17, also known as CTLA-8, stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis. TGF-Beta (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines. IL-17 (~32kDa) protein is produced and exists as a homo-dimer, has homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterzed and highly expressed by activated effector memory T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-27327AF350
Alexa Fluor 405 NBP2-27327AF405
Alexa Fluor 488 NBP2-27327AF488
Alexa Fluor 532 NBP2-27327AF532
Alexa Fluor 594 NBP2-27327AF594
Alexa Fluor 647 NBP2-27327AF647
Alexa Fluor 700 NBP2-27327AF700
Alexa Fluor 750 NBP2-27327AF750
Biotin NBP2-27327B
DyLight 350 NBP2-27327UV
DyLight 405 NBP2-27327V
DyLight 488 NBP2-27327G
DyLight 550 NBP2-27327R
DyLight 594 NBP2-27327DL594
DyLight 650 NBP2-27327C
DyLight 680 NBP2-27327FR
DyLight 755 NBP2-27327IR
FITC NBP2-27327F
HRP NBP2-27327H
Janelia Fluor 549 NBP2-27327JF549
Janelia Fluor 646 NBP2-27327JF646

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Bioinformatics

Gene Symbol IL17F
Entrez
Uniprot