IL-1 beta/IL-1F2 Antibody (43N3D8)


Western Blot: IL-1 beta/IL-1F2 Antibody (43N3D8) [NBP2-27345] - Analysis of full length human IL-1 beta recombinant protein (10ng/well) using IL1 beta Antibody (NBP2-27345) at 1:1000 (left lane) and 1:100 (right lane).
Immunohistochemistry-Paraffin: IL-1 beta/IL-1F2 Antibody (43N3D8) [NBP2-27345] - Analysis of Interleukin-1 beta in human kidney tissue using Interleukin-1 beta antibody at 5 ug/ml.
Flow Cytometry: IL-1 beta/IL-1F2 Antibody (43N3D8) [NBP2-27345] - Intracellular staining of Interleukin-1 beta positive T cells (upper panel) & monocytes (lower panel) from stimulated PBMC (with a cocktail of TLR more
Western Blot: IL-1 beta/IL-1F2 Antibody (43N3D8) [NBP2-27345] - Analysis of Interleukin-1 beta in A) full-length recombinant protein and B) human ThP1 lysate using Interleukin-1 beta antibody at 1 ug/ml and 5 ug/ml, more

Product Details

Reactivity HuSpecies Glossary
Applications WB, Flow, IHC-P
0.5 mg/ml

IL-1 beta/IL-1F2 Antibody (43N3D8) Summary

Full-length recombinant human Interleukin-1 beta protein was used as immunogen for this antibody.
IgG1 Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1 mg antibody in 0.2 ml PBS containing 0.05% BSA.
0.05% Sodium Azide
0.5 mg/ml
Protein G purified


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NBP2-27345 in the following applications:

  • WB
    1 publication

Reactivity Notes


Alternate Names for IL-1 beta/IL-1F2 Antibody (43N3D8)

  • catabolin
  • IL1 beta
  • IL-1 beta
  • IL-1
  • IL1B
  • IL-1B
  • IL1-BETA
  • IL-1F2
  • IL1F2IL-1 beta
  • interleukin 1, beta
  • interleukin-1 beta
  • preinterleukin 1 beta
  • pro-interleukin-1-beta


IL-1beta (Interleukin-1 beta, IL-1) is a potent inflammatory cytokine which has been well studied. Produced as a precursor, especially in myeloid cells and monocytes/macrophages, Interleukin-1 beta is processed by cleavage with caspase-1, or ICE, from the 31 kD inactive precursor to the 18kD active mature form secreted from cells as an end-result of the inflammasome complex and activation sequence (1, 2). In response to various TLR ligands, myeloid cells or macrophages activate NLRP3 inflammasomes and secrete Interleukin-1 beta. The rate of Interleukin-1 beta processing has been correlated to redox state or levels of ROS generated (3, 4). Interleukin-1 beta is directly involved in a variety of diseases-auto-inflammatory diseases, acute inflammatory attacks such as ischemic injury in myocardial infarcts or in chronic inflammatory processes of atherosclerosis or Type 2 diabetes (5, 6). The ability to detect and quantitate active Interleukin-1 beta is critical for understanding how to regulate its activity as a therapeutic target.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IL-1 beta/IL-1F2 Antibody (NBP2-27345)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP2-27345AF405
Alexa Fluor (R) 488 Labeled NBP2-27345AF488
Alexa Fluor (R) 647 Labeled NBP2-27345AF647
Alexa Fluor (R) 700 Labeled NBP2-27345AF700
Allophycocyanin Labeled NBP2-27345APC
Biotin Labeled NBP2-27345B
DyLight 350 Labeled NBP2-27345UV
DyLight 405 Labeled NBP2-27345V
DyLight 405LS Labeled NBP2-27345V3
DyLight 488 Labeled NBP2-27345G
DyLight 550 Labeled NBP2-27345R
DyLight 650 Labeled NBP2-27345C
DyLight 680 Labeled NBP2-27345FR
DyLight 755 Labeled NBP2-27345IR
HRP Labeled NBP2-27345H
PE Labeled NBP2-27345PE
PerCP Labeled NBP2-27345PCP

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Diseases for IL-1 beta/IL-1F2 Antibody (NBP2-27345)

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Blogs on IL-1 beta/IL-1F2.

IL-1 beta (interleukin 1 beta, lymphocyte activating factor (LAF))
IL-1 was originally identified and cloned as a lymphocyte mitogen and much later, was found to be comprised of two closely related but distinct proteins, interleukin 1 alpha (IL-1 alpha) and interleukin 1 beta (IL-1 beta). Both these proteins bind...  Read full blog post.

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Product PDFs


Gene Symbol IL1B

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