IL-1 alpha/IL-1F1 Antibody (3405) [PerCP]

• Reactivity: Hu
• Applications: Flow, B/N, CyTOF-ready
• Clone: 3405
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PerCP

IL-1 alpha/IL-1F1 Antibody (3405) [PerCP] Summary

• Immunogen: E. coli-derived recombinant human IL‑1 alpha /IL‑1F1
  Ser113-Ala271
  Accession # P01583
• Specificity: Detects human IL‑1 alpha /IL‑1F1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse IL-1 alpha , recombinant rat IL-1 alpha , recombinant cotton rat IL-1 alpha , recombinant human (rh) IL-1 beta or rhIL-18 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL1A
• Purity: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from ascites

Alternate Names for IL-1 alpha/IL-1F1 Antibody (3405) [PerCP]

• BAF
• Hematopoietin-1
• IL1 alpha
• IL-1 alpha
• IL1
• IL1A
• IL-1A
• IL1-ALPHA
• IL1F1
• IL-1F1
• IL1F1hematopoietin-1
• interleukin 1, alpha
• interleukin-1 alpha
• LAF
• LEM
• preinterleukin 1 alpha
• pro-interleukin-1-alpha

Background

Interleukin-1 alpha (IL-1a, lymphocyte activating factor (LAF), hematopoietin-1, endogeneous pyrogen, mononuclear cell factor) is a pleiotropic pro-inflammatory cytokine produced in a variety of cells, including monocytes, macrophages and epithelial cells. It is involved in inflammatory and immune responses and regulation of hematopoiesis. It may therefore be of clinical use following massive immunosuppression and chemotherapy. Recombinant human IL-1a is a single non-glycosylated polypetide chain of 159 amino acids with a MW of 18 kDa. Sequence conservation of the mature protein among various species is 60% -70%, human IL-1 has been found to be biologically active on murine cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL1A