IL-1 alpha/IL-1F1 Products

Description

Interleukin-1 alpha (IL-1a, lymphocyte activating factor (LAF), hematopoietin-1, endogeneous pyrogen, mononuclear cell factor) is a pleiotropic pro-inflammatory cytokine produced in a variety of cells, including monocytes, macrophages and epithelial cells. It is involved in inflammatory and immune responses and regulation of hematopoiesis. It may therefore be of clinical use following massive immunosuppression and chemotherapy. Recombinant human IL-1a is a single non-glycosylated polypetide chain of 159 amino acids with a MW of 18 kDa. Sequence conservation of the mature protein among various species is 60% -70%, human IL-1 has been found to be biologically active on murine cell lines.

Bioinformatics

Entrez	16175 Mouse 24493 Rat 3552 Human
Uniprot	AAH13142 Human NP_000566 Human NP_000566.3 Human P01583 Human Q53QF9 Human Q62161 Mouse Q9NPH3 Human
Product By Gene ID	3552
Alternate Names	Hematopoietin-1 IL-1 alpha IL1 IL-1A IL1-ALPHA IL1F1hematopoietin-1 interleukin 1, alpha interleukin-1 alpha preinterleukin 1 alpha pro-interleukin-1-alpha

Diseases related to IL-1 alpha/IL-1F1

Discover more about diseases related to IL-1 alpha/IL-1F1.

Inflammation
Malignant Neoplasms
Inflammatory Response
Alzheimer's Disease
Variable Number Tandem Repeat
Neoplasms
Dysequilibrium Syndrome
Cholangiocarcinoma
Periodontitis
Arthritis
Carcinogenesis
Spondylitis
Degenerative Polyarthritis
Carcinoma
Tissue Adhesions
Asthma
Ankylosing Spondylitis
Sclerosis
Malignant Neoplasm Of Breast
Mammary Neoplasms

Pathways for IL-1 alpha/IL-1F1

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Pathogenesis
Inflammatory Response
Immune Response
Secretion
Parturition
Wound Healing
Localization
Cytokine Production
Cell Death
Angiogenesis
Cell Adhesion
Cell Activation
Cell Proliferation
Dna Repair
Ovulation
Tissue Homeostasis
Cell Cycle
Innate Immune Response
Cell Migration
Regulation Of Programmed Cell Death

Research Areas for IL-1 alpha/IL-1F1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Biologically Active Proteins
Cytokine Research
Diabetes Research
Immune System Diseases
Immunology
Innate Immunity

PTMs for IL-1 alpha/IL-1F1

Learn more about PTMs related to IL-1 alpha/IL-1F1.

Cleavage
Phosphorylation
Biotinylation
Reduction
Acetylation
Methylation

Bioinformatics Tool for IL-1 alpha/IL-1F1

Discover related pathways, diseases and genes to IL-1 alpha/IL-1F1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.