IKEPP Antibody Pair

Product Discontinued

IKEPP Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-PDZD3 (300 ul)
• Antibody pair for WB: mouse purified polyclonal anti-PDZD3 (50 ug)
• Clonality: Polyclonal
• Gene: PDZD3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for IKEPP Antibody Pair

• FLJ22756
• IKEPPPDZK2
• intestinal and kidney enriched PDZ protein
• Intestinal and kidney-enriched PDZ protein
• Na(+)/H(+) exchange regulatory cofactor NHE-RF4
• Na/Pi cotransporter C-terminal-associated protein 2
• naPi-Cap2
• Natrium-phosphate cotransporter IIa C-terminal-associated protein 2
• NHERF4
• NHERF-4
• PDZ domain containing 2
• PDZ domain containing 3
• PDZ domain-containing protein 2
• PDZ domain-containing protein 3
• Sodium-hydrogen exchanger regulatory factor 4

Background

IKEPP, also known as PDZD3, associates with GUCY2C to act as a regulatory protein and negatively modulates the heat-stable enterotoxin-mediated activation of GUCY2C. Specifically, IKEPP regulates the amount of cGMP produced following receptor stimulation. IKEPP has also been found to stimulate SLC9A3 activity in the presence of elevated calcium ions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PDZD3