IKEPP Products

Description

IKEPP, also known as PDZD3, associates with GUCY2C to act as a regulatory protein and negatively modulates the heat-stable enterotoxin-mediated activation of GUCY2C. Specifically, IKEPP regulates the amount of cGMP produced following receptor stimulation. IKEPP has also been found to stimulate SLC9A3 activity in the presence of elevated calcium ions.

Bioinformatics

Entrez	170761 Mouse 500986 Rat 79849 Human
Uniprot	AAH29042 Human NM_024791 Human NP_079067 Human Q99MJ6 Mouse
Product By Gene ID	79849
Alternate Names	FLJ22756 IKEPPPDZK2 intestinal and kidney enriched PDZ protein Intestinal and kidney-enriched PDZ protein Na(+)/H(+) exchange regulatory cofactor NHE-RF4 Na/Pi cotransporter C-terminal-associated protein 2 NaPi-Cap2 naPi-Cap2 Natrium-phosphate cotransporter IIa C-terminal-associated protein 2 NHERF4 NHERF-4 PDZ domain containing 2 PDZ domain containing 3 PDZ domain-containing protein 2 PDZ domain-containing protein 3 Sodium-hydrogen exchanger regulatory factor 4

Research Areas for IKEPP

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Signal Transduction