IKBKAP Antibody

Images

 
Western Blot: IKBKAP Antibody [NBP2-16936] - Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 5% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: IKBKAP Antibody [NBP2-16936] - HeLa cells were fixed in iced-cold MeOH for 5 min. Green: IKBKAP protein stained by IKBKAP antibody, Internal diluted at 1:500. Blue: Hoechst 33343 ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

IKBKAP Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human IKBKAP. The exact sequence is proprietary.
Localization
Cytoplasm; Nucleus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IKBKAP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
Theoretical MW
150 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IKBKAP Antibody

  • DYS
  • elongator complex protein 1
  • ELP1DKFZp781H1425
  • FD
  • FLJ12497
  • IKAPdysautonomia (Riley-Day syndrome, hereditary sensory autonomic neuropathy typeIII)
  • IkappaB kinase complex-associated protein
  • IKI3
  • IKK complex-associated protein
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinasecomplex-associated protein
  • p150
  • TOT1

Background

The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IKBKAP
Uniprot