IGFBP-3 Antibody (RM0096-11B16)


Western Blot: IGFBP-3 Antibody (RM0096-11B16) [NBP1-22452] - Analysis in mouse placental tissue lysates.

Product Details

Reactivity MuSpecies Glossary
Applications WB
LYOPH mg/ml

Order Details

IGFBP-3 Antibody (RM0096-11B16) Summary

Mouse recombinant protein of IGFBP-3
This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant protein of IGFBP-3.
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.2 um filtered solution in PBS.
Sodium Azide
LYOPH mg/ml
Protein G purified
Reconstitution Instructions
Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.


Application Notes
This antibody detects mouse IGFBP-3 in Western blotting. No cross activity to other mouse IGFBPs. Use Non-reducing conditions.

Alternate Names for IGFBP-3 Antibody (RM0096-11B16)

  • acid stable subunit of the 140 K IGF complex
  • binding protein 29
  • binding protein 53
  • growth hormone-dependent binding protein
  • IBP-3
  • IBP3BP-53
  • IGF-binding protein 3
  • IGFBP3
  • IGFBP-3
  • insulin-like growth factor binding protein 3
  • insulin-like growth factor-binding protein 3


Insulin like growth factor binding protein 3 (IGFBP3) is a member of the superfamily of insulin like growth factor (IGF) binding proteins which include six high affinity IGF binding proteins (IGFBP) and at least four low affinity binding proteins referred to as IGFBP related proteins (IGFBPrP). The IGFBP members are cysteine rich proteins with conserved cysteine residues clustered in the amino terminal and the carboxy terminal regions of the molecule. The cDNA sequence encoding the mature human IGFBP3 is fused to the signal peptide of CD33. Human IGFBP3 is the major IGF binding protein in plasma where it exists in a ternary complex with IGFI or IGFII and an acid labile subunit. IGFBPs hold a central position in IGF ligand-receptor interactions through influences on both the bioavailability and distribution of IGFs in the extracellular environment. Insulin like growth factor binding protein 3 (IGFBP3) can modulate the mitogenic and metabolic effects of the insulin like growth factors (IGFs). Insulin like growth factor binding protein 3 (IGFBP3) is expressed in multiple tissues. The highest expression level is found in the non paranchymal cells of the liver. The expression levels are higher during extrauterine life and peak during puberty. Insulin like growth factors (IGFs) and IGF binding proteins (IGFBPs) play important roles in cell growth and differentiation. IGFBP3 is one of the factors in serum that is responsible for high serum induced apoptosis in PC3 cells, a prostate cancer cell line. IGFBP3 is important in controlling glucose homeostasis with increased urinary levels in type I diabetes with persistent microalbuminuria.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, ELISA(Cap), ELISA(Det), Neut, ELISA(Sta)
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, Flow, IHC, Neut
Species: Mu
Applications: WB
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC-P
Species: Hu
Applications: WB, ELISA(Cap), ELISA(Det), ELISA(Sta)
Species: Hu
Applications: WB, ELISA(Cap), ELISA(Det), Neut, ELISA(Sta)
Species: Mu
Applications: WB

Publications for IGFBP-3 Antibody (NBP1-22452) (0)

There are no publications for IGFBP-3 Antibody (NBP1-22452).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for IGFBP-3 Antibody (NBP1-22452) (0)

There are no reviews for IGFBP-3 Antibody (NBP1-22452). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for IGFBP-3 Antibody (NBP1-22452) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional IGFBP-3 Antibody (RM0096-11B16) Products

Related Products by Gene

Bioinformatics Tool for IGFBP-3 Antibody (NBP1-22452)

Discover related pathways, diseases and genes to IGFBP-3 Antibody (NBP1-22452). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for IGFBP-3 Antibody (NBP1-22452)

Discover more about diseases related to IGFBP-3 Antibody (NBP1-22452).

Pathways for IGFBP-3 Antibody (NBP1-22452)

View related products by pathway.

PTMs for IGFBP-3 Antibody (NBP1-22452)

Learn more about PTMs related to IGFBP-3 Antibody (NBP1-22452).

Research Areas for IGFBP-3 Antibody (NBP1-22452)

Find related products by research area.

Blogs on IGFBP-3

There are no specific blogs for IGFBP-3, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol IGFBP3

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-22452 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought