IGFBP-2 Antibody (CL13565) [DyLight 650]

• Reactivity: Hu
• Applications: IHC
• Clone: CL13565
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

IGFBP-2 Antibody (CL13565) [DyLight 650] Summary

• Immunogen: This antibody was generated using a synthetic peptide of P18065, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: IGFBP2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IGFBP-2 Antibody (CL13565) [DyLight 650]

• BP2
• IBP2
• IBP-2
• IGF-binding protein 2
• IGFBP2
• IGFBP-2
• IGF-BP53
• insulin-like growth factor binding protein 2 (36kD)
• insulin-like growth factor binding protein 2, 36kDa
• insulin-like growth factor-binding protein 2

Background

IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is over expressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The over expression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IGFBP2