IgE Antibody (BE5)

Images

 
Flow Cytometry: IgE Antibody (BE5) [NB500-470] - Flow Cytometry analysis of basophil activation upon stimulation of normal (heparin-treated) whole blood with combination of IL-3 and Goat anti-IgE polyclonal antibody. ...read more
Flow Cytometry: IgE Antibody (BE5) [NB500-470] - Surface staining of IgE in human peripheral blood lymphocytes with anti-IgE (BE5) purified, GAM-APC.
Flow Cytometry: IgE Antibody (BE5) [NB500-470] - Analysis of basophil activation upon stimulation of normal (heparin-treated) whole blood with combination of IL-3 and Goat anti-IgE polyclonal antibody. Fig. 1B - ...read more
Flow Cytometry: IgE Antibody (BE5) [NB500-470] - Surface staining of IgE in human peripheral blood with anti-IgE (BE5) PE.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow
Clone
BE5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

IgE Antibody (BE5) Summary

Immunogen
Purified human IgE.
Specificity
The antibody BE5 reacts with human IgE; it recognizes an epitope different from the ones recognized by 4G7 and 4H10 antibodies to IgE.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGHE
Purity
Ion exchange chromatography
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:2000
  • Flow Cytometry
Publications
Read Publication using NB500-470.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1 mg/ml
Purity
Ion exchange chromatography

Alternate Names for IgE Antibody (BE5)

  • IgE
  • immunoglobulin heavy constant epsilon

Background

Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IgE Antibody (NB500-470)(1)

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Secondary Antibodies

 

Isotype Controls

Additional IgE Products

Bioinformatics Tool for IgE Antibody (NB500-470)

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Diseases for IgE Antibody (NB500-470)

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Blogs on IgE.

Understanding the Importance of Human IgG
Human IgG is a component of the immune system that protects the body from infection. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains...  Read full blog post.

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Bioinformatics

Gene Symbol IGHE