Applications: ELISA, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Applications: Flow, Flow-CS, Flow-IC, IHC, IHC-Fr, IHC-P, ICC/IF
Host: Human Polyclonal
Host: Rat Monoclonal
IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.
|Product By Gene ID
- immunoglobulin heavy constant epsilon
Research Areas for IgE
Find related products by research area and learn more about each of the different research areas below.Adaptive ImmunityImmunology
Bioinformatics Tool for IgE
Discover related pathways, diseases and genes to IgE. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Related IgE Blog Posts
Check out the latest blog posts on IgE.
Read more IgE related blogs.
|Understanding the Importance of Human IgG
Human IgG is a component of the immune system that protects the body from infection. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains ... Read more.