IDI1 Antibody

Images

 
Western Blot: IDI1 Antibody [NBP1-31477] - Sample (30 ug of whole cell lysate) A: Molt-4 12% SDS PAGE, antibody diluted at 1:3000.
Immunohistochemistry-Paraffin: IDI1 Antibody [NBP1-31477] - Paraffin-embedded SCC15 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.65 mg/ml

Order Details

IDI1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human IDI1. The exact sequence is proprietary.
Localization
Peroxisome
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IDI1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Mouse (87%), Rat (86%), Xenopus laevis (80%), Bovine (89%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.65 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IDI1 Antibody

  • EC 5.3.3.2
  • IPP isomerase 1
  • IPP1
  • IPPI1
  • isopentenyl diphosphate dimethylallyl diphosphate isomerase 1
  • Isopentenyl pyrophosphate isomerase 1
  • isopentenyl-diphosphate delta isomerase 1
  • isopentenyl-diphosphate delta isomerase
  • isopentenyl-diphosphate Delta-isomerase 1

Background

IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for IDI1 Antibody (NBP1-31477)

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Bioinformatics

Gene Symbol IDI1