IDI1 Products

Description

IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.

Bioinformatics

Entrez	3422 Human
Uniprot	AAH05247 Human AAH57827 Human AAH57827.1 Human NP_004499 Human Q13907 Human
Product By Gene ID	3422
Alternate Names	EC 5.3.3.2 IPP isomerase 1 IPP1 IPPI1 isopentenyl diphosphate dimethylallyl diphosphate isomerase 1 Isopentenyl pyrophosphate isomerase 1 isopentenyl-diphosphate delta isomerase 1 isopentenyl-diphosphate delta isomerase isopentenyl-diphosphate Delta-isomerase 1