Human VEGFR1/Flt-1 Quantikine ELISA Kit, NEW

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human VEGFR1/Flt-1 Quantikine ELISA Kit, NEW Summary

Background
The Quantikine® Human VEGF R1/Flt-1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human VEGF R1 in cell culture supernates, cell lysates, serum, plasma, and saliva. It contains NS0-expressed recombinant human VEGF R1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human VEGF R1 showed linear curves that were par...allel to the standard curves obtained using the Quantikine® kit standards. These results indicate that this kit can be used to determine relative mass values for natural human VEGF R1.
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Specificity
Natural and recombinant human VEGF R1.
Source
N/A
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DVR100C.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human VEGFR1/Flt-1 Quantikine ELISA Kit, NEW

  • EC 2.7.10
  • EC 2.7.10.1
  • FLT
  • FLT1
  • Flt-1
  • Fms-like tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
  • FRT
  • Tyrosine-protein kinase FRT
  • Tyrosine-protein kinase receptor FLT
  • vascular endothelial growth factor receptor 1
  • Vascular permeability factor receptor
  • VEGF R1
  • VEGFR1
  • VEGFR-1

Background

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for VEGFR1/Flt-1 (DVR100C)(88)

We have publications tested in 3 confirmed species: Human, Mouse, Rabbit.


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Human
(85)
Mouse
(4)
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(1)
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Showing Publications 1 - 10 of 88. Show All 88 Publications.
Publications using DVR100C Applications Species
Moon, SY;Kim, HJ;Kim, JK;Kim, J;Choi, JS;Won, SY;Park, K;Lee, SHS; An examination of the mechanisms driving the therapeutic effects of an AAV expressing a soluble variant of VEGF receptor-1 PloS one 2024-07-11 [PMID: 38990973] (Human) Human
Mäenpää, N;Tiainen, L;Hämäläinen, M;Luukkaala, T;Tanner, M;Lahdenperä, O;Vihinen, P;Karihtala, P;Kellokumpu-Lehtinen, PL;Moilanen, E;Jukkola, A; Neuropilin-1 and placental growth factor as prognostic factors in metastatic breast cancer BMC cancer 2024-03-11 [PMID: 38468231] (Human) Human
Donohue, JK;Gruen, DS;Iyanna, N;Lorence, JM;Brown, JB;Guyette, FX;Daley, BJ;Eastridge, BJ;Miller, RS;Nirula, R;Harbrecht, BG;Claridge, JA;Phelan, HA;Vercruysse, GA;O'Keeffe, T;Joseph, B;Neal, MD;Billiar, TR;Sperry, JL; Mechanism matters: mortality and endothelial cell damage marker differences between blunt and penetrating traumatic injuries across three prehospital clinical trials Scientific reports 2024-02-02 [PMID: 38302619] (Human) Human
Zhao, J;Duan, R;Sun, J;Chow, RP;Lyons, TJ;Yu, JY; An Examination of the Effect of Aspirin and Salicylic Acid on Soluble Fms-like Tyrosine Kinase-1 Release from Human Placental Trophoblasts Cells 2024-01-06 [PMID: 38247805] (Human) Human
Pintye, D;Sziva, RE;Mastyugin, M;Young, BC;Jacas, S;Török, M;Salahuddin, S;Jagtap, P;Southan, GJ;Zsengellér, ZK; A Novel Dual-Function Redox Modulator Relieves Oxidative Stress and Anti-Angiogenic Response in Placental Villus Explant Exposed to Hypoxia-Relevance for Preeclampsia Therapy Biology 2023-09-12 [PMID: 37759628] (Human) Human
Yang, Z;Jia, X;Deng, Q;Luo, M;Hou, Y;Yue, J;Mei, J;Shan, N;Wu, Z; Human umbilical cord mesenchymal stem cell-derived extracellular vesicles loaded with TFCP2 activate Wnt/?-catenin signaling to alleviate preeclampsia International immunopharmacology 2023-02-01 [PMID: 37724958] (Human) Human
X Huang, L Jia, Y Jia, X Xu, R Wang, M Wei, H Li, H Peng, Y Wei, Q He, K Wang sFlt-1-enriched exosomes induced endothelial cell dysfunction and a preeclampsia-like phenotype in mice Cytokine, 2023-04-14;166(0):156190. 2023-04-14 [PMID: 37062152] (Human, Mouse) Human, Mouse
X Liu, Z Li, J Sun, Z Zhang, W Li Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophages BMC Cancer, 2023-03-20;23(1):259. 2023-03-20 [PMID: 36941554] (Human) Human
LO Kurlak, PJ Scaife, LV Briggs, F Broughton, DS Gardner, HD Mistry Alterations in Antioxidant Micronutrient Concentrations in Placental Tissue, Maternal Blood and Urine and the Fetal Circulation in Pre-eclampsia International Journal of Molecular Sciences, 2023-02-10;24(4):. 2023-02-10 [PMID: 36834991] (Human) Human
W Dymara-Kon, M Laskowska, E Grywalska, A Hymos, A B?a?ewicz, B Leszczy?sk Similar Pro- and Antiangiogenic Profiles Close to Delivery in Different Clinical Presentations of Two Pregnancy Syndromes: Preeclampsia and Fetal Growth Restriction International Journal of Molecular Sciences, 2023-01-04;24(2):. 2023-01-04 [PMID: 36674486] (Human) Human
Show All 88 Publications.

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