Human Urinary TIM-1/KIM-1/HAVCR Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Catalog# & Conjugate Size Price

Human Urinary TIM-1/KIM-1/HAVCR Quantikine ELISA Kit Summary

Background
The Quantikine Human TIM-1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TIM-1 in urine. It contains NS0-expressed recombinant human TIM-1 and antibodies raised against the recombinant factor. Natural human TIM-1 showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards, indicating that this kit can be used to determine relative levels of natural human TIM-1.
Specificity
Natural and recombinant human TIM-1
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
HAVCR1

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DKM100.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Urinary TIM-1/KIM-1/HAVCR Quantikine ELISA Kit

  • CD365
  • HAVCR1
  • HAVCR-1
  • HAVCRT cell immunoglobin domain and mucin domain protein 1
  • hepatitis A virus cellular receptor 1
  • Kidney injury molecule 1
  • KIM1
  • KIM-1
  • T-cell immunoglobulin and mucin domain-containing protein 1
  • TIM1
  • TIM-1
  • TIM-1TIM
  • TIM1TIMD-1
  • TIMD1T-cell membrane protein 1

Background

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for TIM-1/KIM-1/HAVCR (DKM100)(17)

We have publications tested in 2 confirmed species: Human, Rat.


Filter By Application
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Human
(16)
Rat
(1)
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Showing Publications 1 - 10 of 17. Show All 17 Publications.
Publications using DKM100 Applications Species
W Wo?yniec, K Kasprowicz, J Giebu?towi, N Korytowska, K Zorena, M Bartoszewi, P Rita-Tkach, M Renke, W Ratkowski Changes in Water Soluble Uremic Toxins and Urinary Acute Kidney Injury Biomarkers After 10- and 100-km Runs Int J Environ Res Public Health, 2019;16(21):. 2019 [PMID: 31661892] (Human) Human
R Jouffroy, X Lebreton, N Mansencal, D Anglicheau Acute kidney injury during an ultra-distance race PLoS ONE, 2019;14(9):e0222544. 2019 [PMID: 31553742] (Human) Human
T Gohda, N Kamei, T Koshida, M Kubota, K Tanaka, Y Yamashita, E Adachi, S Ichikawa, M Murakoshi, S Ueda, Y Suzuki Circulating kidney injury molecule-1 as a biomarker of renal parameters in diabetic kidney disease J Diabetes Investig, 2019;0(0):. 2019 [PMID: 31483944] (Human) Human
Y Huang, Y Tian, S Likhodii, E Randell Baseline urinary KIM-1 concentration in detecting acute kidney injury should be interpreted with patient pre-existing nephropathy Pract Lab Med, 2019;15(0):e00118. 2019 [PMID: 30989103] (Human) Human
D Kostic, GPNS Beozzo, SB do Couto, AHT Kato, L Lima, P Palmeira, VLJ Krebs, V Bunduki, RPV Francisco, M Zugaib, FT Dénes, WB de Carvalh, VHK Koch The role of renal biomarkers to predict the need of surgery in congenital urinary tract obstruction in infants J Pediatr Urol, 2019;0(0):. 2019 [PMID: 30979613] (Human) Human
QQ Jiang, MF Han, K Ma, G Chen, XY Wan, SB Kilonzo, WY Wu, YL Wang, J You, Q Ning Acute kidney injury in acute-on-chronic liver failure is different from in decompensated cirrhosis World J. Gastroenterol., 2018;24(21):2300-2310. 2018 [PMID: 29881239] (Human) Human
JJ Wang, NH Chi, TM Huang, R Connolly, LW Chen, SJ Chueh, WC Kan, CC Lai, VC Wu, JT Fang, TS Chu, KD Wu Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery Crit Care, 2018;22(1):108. 2018 [PMID: 29699579] (Human) Human
SAE Dayem, AEME Bohy, M Hamed, S Ahmed Follow Up of Value of the Intrarenal Resistivity Indices and Different Renal Biomarkers for Early Identification of Diabetic Nephropathy in Type 1 Diabetic Patients Open Access Maced J Med Sci, 2017;5(2):188-192. 2017 [PMID: 28507626] (Human) Human
Y Jin, X Shao, B Sun, C Miao, Z Li, Y Shi Urinary kidney injury molecule?1 as an early diagnostic biomarker of obstructive acute kidney injury and development of a rapid detection method Mol Med Rep, 2017;0(0):. 2017 [PMID: 28075469] (Rat) Rat
Jongman R, van Klarenbosch J, Molema G, Zijlstra J, de Vries A, van Meurs M Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass. PLoS ONE, 2015;10(8):e0136205. 2015 [PMID: 26309217] (Human) Human
Show All 17 Publications.

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Product General Protocols

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FAQs for TIM-1/KIM-1/HAVCR (DKM100). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DKM100
HRP SKM100

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Bioinformatics

Gene Symbol HAVCR1