Human TREM-1 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human TREM-1 Quantikine ELISA Kit Summary

Background
The Quantikine Human TREM-1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TREM-1 levels in cell culture supernates, cell lysates, serum, plasma, and saliva. It contains NS0-expressed recombinant human TREM-1 and antibodies raised against the recombinant protein. Results obtained for naturally occurring human TREM-1 showed linear curves that were parallel to the standard cur...ves obtained using the Quantikine Human TREM-1 Immunoassay standards. These results indicate that this kit can be used to determine relative mass values for natural human TREM-1.
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Specificity
Natural and recombinant human TREM-1.
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
TREM1

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DTRM10C.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human TREM-1 Quantikine ELISA Kit

  • CD354 antigen
  • CD354
  • TREM1
  • TREM-1
  • TREM-1Triggering receptor expressed on monocytes 1
  • triggering receptor expressed on myeloid cells 1
  • triggering-receptor TREM1

Background

The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. The receptors are members of the immunoglobulin superfamily, characterized structurally by a single V-set immunoglobulin (Ig) domain and a short cytoplasmic tail. TREMs associate with the DAP12 signal adapter, an immunoreceptor tyrosine-based activation motif- (ITAM)-containing protein that is phosphorylated and transduces signals when activated.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for TREM1 (DTRM10C)(13)

We have publications tested in 1 confirmed species: Human.


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Human
(13)
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Showing Publications 1 - 10 of 13. Show All 13 Publications.
Publications using DTRM10C Applications Species
AH de Nooijer, I Grondman, S Lambden, EJ Kooistra, NA Janssen, M Kox, P Pickkers, LA Joosten, F van de Vee, M Derive, S Gibot, MG Netea Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19 Bioscience Reports, 2021;0(0):. 2021 [PMID: 34195785] (Human) Human
W Chang, F Peng, SS Meng, JY Xu, Y Yang Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis BMC Immunol., 2020;21(1):2. 2020 [PMID: 31931717] (Human) Human
Y He, Q Yang, X Wang, A Jia, W Xie, J Zhou Inhibition of Triggering Receptor Expressed on Myeloid Cell-1 Alleviates Acute Gouty Inflammation Mediators Inflamm., 2019;2019(0):5647074. 2019 [PMID: 31885496] (Human) Human
J Hyun, RS McMahon, AL Lang, JS Edwards, AD Badilla, ME Greene, GW Stone, S Pallikkuth, M Stevenson, DM Dykxhoorn, S Kottilil, S Pahwa, E Thomas HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells PLoS Pathog., 2019;15(7):e1007883. 2019 [PMID: 31260499] (Human) Human
JY Feng, WJ Su, SW Pan, YC Yeh, YY Lin, NJ Chen Role of TREM-1 in pulmonary tuberculosis patients- analysis of serum soluble TREM-1 levels Sci Rep, 2018;8(1):8223. 2018 [PMID: 29844416] (Human) Human
AA Arguinano, NC Ndiaye, C Masson, S Visvikis-S Pleiotropy of ABO gene: correlation of rs644234 with E-selectin and lipid levels Clin. Chem. Lab. Med., 2018;0(0):. 2018 [PMID: 29373315] (Human) Human
AA Aldasoro A, S Dadé, M Stathopoul, M Derive, N Coumba Ndi, T Xie, C Masson, S Gibot, S Visvikis-S TREM-1 SNP rs2234246 regulates TREM-1 protein and mRNA levels and is associated with plasma levels of L-selectin PLoS ONE, 2017;12(8):e0182226. 2017 [PMID: 28771614] (Human) Human
E Sierra-Dia, A Bravo Cuél, PC Ortiz Laza, M García Gut, HF Georgina, R Anaya Prad Urine TREM-1 as a marker of urinary tract infection in children J. Int. Med. Res., 2017;45(2):631-638. 2017 [PMID: 28367708] (Human) Human
Chen CY, Yang KY, Chen MY, Chen HY, Lin MT, Lee YC, Perng RP, Hsieh SL, Yang PC, Chou TY Decoy receptor 3 levels in peripheral blood predict outcomes of acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med., 2009;180(8):751-60. 2009 [PMID: 19644047] (Human) Human
Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, Kohsaka H Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis. Arthritis Rheum., 2009;60(6):1615-23. 2009 [PMID: 19479878] (Human) Human
Show All 13 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for TREM1 (DTRM10C). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DTRM10C

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Bioinformatics Tool for TREM1 (DTRM10C)

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Blogs on TREM1.

TREM1: An inflammatory signal protein with a potential role in cancer
TREM1 is pro-inflammatory gene that stimulates neutrophil and monocyte-mediated inflammatory responses. This protein is highly expressed in adult liver, lung and spleen. It is also present in the lymph node, spinal cord and heart tissues. TREM-1 plays...  Read full blog post.

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Bioinformatics

Gene Symbol TREM1