TREML1/TLT-1 Antibody - BSA Free

Immunohistochemistry-Paraffin: TREML1/TLT-1 Antibody [NBP1-84234] - Staining in human bone marrow and colon tissues using anti-TREML1 antibody. Corresponding TREML1 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: TREML1/TLT-1 Antibody [NBP1-84234] - Staining of human bone marrow, colon, kidney and testis using Anti-TREML1 antibody NBP1-84234 (A) shows similar protein distribution across tissues to independent antibody NBP1-84235 (B).

Immunohistochemistry-Paraffin: TREML1/TLT-1 Antibody [NBP1-84234] - Staining of human testis.

Immunohistochemistry-Paraffin: TREML1/TLT-1 Antibody [NBP1-84234] - Staining of human bone marrow shows high expression.

Immunohistochemistry-Paraffin: TREML1/TLT-1 Antibody [NBP1-84234] - Staining of human colon shows low expression as expected.

Immunohistochemistry-Paraffin: TREML1/TLT-1 Antibody [NBP1-84234] - Staining of human kidney.

Analysis in control (vector only transfected HEK293T lysate) and TREML1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY406014).

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

TREML1/TLT-1 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: APVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQPLVSSAVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQILHRVSLNILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQD
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TREML1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  TREML1/TLT-1 Recombinant Protein Antigen (NBP1-84234PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for TREML1/TLT-1 Antibody - BSA Free

• dJ238O23.3
• GLTL1825
• PRO3438
• TLT1
• TLT-1
• TLT1MGC119173
• TREML1
• trem-like transcript 1 protein
• triggering receptor expressed on myeloid cells-like 1
• Triggering receptor expressed on myeloid cells-like protein 1

Background

TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1(MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calciumsignaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 (PubMed 12645956); Barrow et al.,2004 (PubMed 15128762)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TREML1