Human TREM-1 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human TREM-1 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: TREM1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human TREM-1 DuoSet ELISA, 15 Plate

• CD354 antigen
• CD354
• TREM1
• TREM-1
• TREM-1Triggering receptor expressed on monocytes 1
• triggering receptor expressed on myeloid cells 1
• triggering-receptor TREM1

Background

The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. The receptors are members of the immunoglobulin superfamily, characterized structurally by a single V-set immunoglobulin (Ig) domain and a short cytoplasmic tail. TREMs associate with the DAP12 signal adapter, an immunoreceptor tyrosine-based activation motif- (ITAM)-containing protein that is phosphorylated and transduces signals when activated.

Publications for TREM1 (DY1278B)(17)

Publications using DY1278B

• de Jesus, MCS;Cerilo-Filho, M;Ramirez, ADR;Menezes, RAO;Gomes, MSM;Cassiano, GC;Gurgel, RQ;Silva, JRS;Moura, TR;Pratt-Riccio, LR;Baptista, ARS;Storti-Melo, LM;Machado, RLD; Influence of trem-1 gene polymorphisms on cytokine levels during malaria by Plasmodium vivax in a frontier area of the Brazilian Amazon Cytokine 2023-06-14 [PMID: 37327529] (Human)
• JCS de Carvalh, PV da Silva-N, DM Toro, CA Fuzo, V Nardini, VE Pimentel, MM Pérez, TFC Fraga-Silv, CNS Oliveira, AM Degiovani, FM Ostini, MR Feitosa, RS Parra, JJR da Rocha, O Feres, FC Vilar, GG Gaspar, IKFM Santos, APM Fernandes, SR Maruyama, EMS Russo, VLD Bonato, CRB Cardoso, M Dias-Baruf, LH Faccioli, CA Sorgi, On Behalf The Interplay among Glucocorticoid Therapy, Platelet-Activating Factor and Endocannabinoid Release Influences the Inflammatory Response to COVID-19 Viruses, 2023-02-19;15(2):. 2023-02-19 [PMID: 36851787] (Human)
• GS Gonçalves, S Correa-Sil, Y Zheng, I Avelar, MM Montenegro, AEF Ferreira, V Bain, TT Fink, P Suguita, C Astley, L Lindoso, F Martins, OM Matsuo, JCOA Ferreira, I Firigato, F de Toledo, M Fernanda B, C Artur A da, M Carneiro-S, HHS Marques, P Palmeira Circulating sTREM-1 as a predictive biomarker of pediatric multisystemic inflammatory syndrome (MIS-C) Cytokine, 2022-11-18;161(0):156084. 2022-11-18 [PMID: 36403563] (Human)
• MCS de Jesus, JHR Barbosa, RAO Menezes, MDSM Gomes, LGS Bomfim, TS Pimenta, ARS Baptista, RLD Machado, TR de Moura, LM Storti-Mel Soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) and other inflammatory mediators in malaria by Plasmodium vivax during enteroparasites coinfection PLoS ONE, 2022-06-24;17(6):e0270007. 2022-06-24 [PMID: 35749690] (Human)
• PV da Silva-N, JCS de Carvalh, VE Pimentel, MM Pérez, DM Toro, TFC Fraga-Silv, CA Fuzo, CNS Oliveira, LC Rodrigues, JGM Argolo, I Carmona-Ga, NT Neto, COS Souza, TM Fernandes, VAF Bastos, AM Degiovani, LF Constant, FM Ostini, MR Feitosa, RS Parra, FC Vilar, GG Gaspar, JJR da Rocha, O Feres, FG Frantz, RF Gerlach, SR Maruyama, EMS Russo, AL Viana, APM Fernandes, IKFM Santos, VLD Bonato, AL Boechat, A Malheiro, RT Sadikot, M Dias-Baruf, CRB Cardoso, LH Faccioli, CA Sorgi, On Behalf sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity Viruses, 2021-12-15;13(12):. 2021-12-15 [PMID: 34960790] (Human)
• S Shiber, V Kliminski, K Orvin, I Sagy, M Vaturi, R Kornowski, M Drescher, Y Molad Elevated Plasma Soluble Triggering Receptor Expressed on Myeloid Cells-1 Level in Patients with Acute Coronary Syndrome (ACS): A Biomarker of Disease Severity and Outcome Mediators of Inflammation, 2021-03-15;2021(0):8872686. 2021-03-15 [PMID: 33814983] (Human)
• TT Klein, E Kohn, B Klin, T Ziv-Baran, E Kozer, M Berkovitch, I Abu Kishk sTREM-1 assessment as a diagnostic biomarker for suspected acute appendicitis in children Asian journal of surgery, 2021-03-23;0(0):. 2021-03-23 [PMID: 33766532] (Human)
• N Inanc, G Mumcu, M Can, M Yay, A Silbereise, D Manoil, H Direskenel, N Bostanci Elevated serum TREM-1 is associated with periodontitis and disease activity in rheumatoid arthritis Scientific Reports, 2021-02-03;11(1):2888. 2021-02-03 [PMID: 33536478] (Human)
• F Ortiz, KM Nylund, H Ruokonen, JH Meurman, J Furuholm, N Bostanci, T Sorsa Salivary Biomarkers of Oral Inflammation Are Associated With Cardiovascular Events and Death Among Kidney Transplant Patients Transplant. Proc., 2020-08-04;0(0):. 2020-08-04 [PMID: 32768288] (Human)
• W Chang, F Peng, SS Meng, JY Xu, Y Yang Diagnostic value of serum soluble triggering expressed receptor on myeloid cells 1 (sTREM-1) in suspected sepsis: a meta-analysis BMC Immunol., 2020-01-13;21(1):2. 2020-01-13 [PMID: 31931717] (Human)
• CMP Vázquez, JO Costa, LGS Bomfim, LV Pires, DG da Silva, KF Fukutani, AR de Jesus, N de Jesus S, G de Jesus S, TR de Moura, K Barbosa Oxidized Low-Density Lipoprotein (Ox-LDL) and Triggering Receptor-Expressed Myeloid Cell (TREM-1) Levels Are Associated with Cardiometabolic Risk in Nonobese, Clinically Healthy, and Young Adults Oxid Med Cell Longev, 2019-02-28;2019(0):7306867. 2019-02-28 [PMID: 30944697] (Human)
• Y Edel, V Kliminski, E Pokroy-Sha, S Oren, A Dortort La, Y Pri-Paz Ba, M Egbaria, Y Molad Elevated plasma level of soluble triggering receptor expressed on myeloid cells-1 is associated with inflammation activity and is a potential biomarker of thrombosis in primary antiphospholipid syndrome Arthritis Res. Ther., 2019-01-07;21(1):10. 2019-01-07 [PMID: 30616644] (Human)
• AA Arguinano, NC Ndiaye, C Masson, S Visvikis-S Pleiotropy of ABO gene: correlation of rs644234 with E-selectin and lipid levels Clin. Chem. Lab. Med., 2018-04-25;0(0):. 2018-04-25 [PMID: 29373315] (Human)
• Lopez-Collazo E, Jurado T, de Dios Caballero J, Perez-Vazquez M, Vindel A, Hernandez-Jimenez E, Tamames J, Cubillos-Zapata C, Manrique M, Tobes R, Maiz L, Canton R, Baquero F, Del Campo R In vivo attenuation and genetic evolution of a ST247-SCCmecI MRSA clone after 13 years of pathogenic bronchopulmonary colonization in a patient with cystic fibrosis: implications of the innate immune response. Mucosal Immunol, 2014-08-13;8(2):362-71. 2014-08-13 [PMID: 25118167] (Human)
• Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM-1-PI3K-NF-kappaB pathway. J. Cell. Sci., 2012-03-29;91(6):933-45. 2012-03-29 [PMID: 22459945] (Human)
• Erdman LK, Dhabangi A, Musoke C, Conroy AL, Hawkes M, Higgins S, Rajwans N, Wolofsky KT, Streiner DL, Liles WC, Cserti-Gazdewich CM, Kain KC Combinations of Host Biomarkers Predict Mortality among Ugandan Children with Severe Malaria: A Retrospective Case-Control Study. PLoS ONE, 2011-02-25;6(2):e17440. 2011-02-25 [PMID: 21364762] (Human)
• Gomez-Pina V, Soares-Schanoski A, Rodriguez-Rojas A, Del Fresno C, Garcia F, Vallejo-Cremades MT, Fernandez-Ruiz I, Arnalich F, Fuentes-Prior P, Lopez-Collazo E Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes. J. Immunol., 2007-09-15;179(6):4065-73. 2007-09-15 [PMID: 17785845] (Human)

FAQs for TREM1 (DY1278B). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: TREM1