Human TL1A/TNFSF15 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human TL1A/TNFSF15 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human TL1A/TNFSF15 DuoSet ELISA, 5 Plate

• MGC129934
• MGC129935
• TL1A
• TL1Vascular endothelial cell growth inhibitor
• TNF superfamily ligand TL1A
• TNFSF15
• tumor necrosis factor (ligand) superfamily, member 15
• tumor necrosis factor ligand superfamily member 15
• vascular endothelial growth inhibitor-192A
• VEGI
• VEGI192A
• VEGITNF ligand-related molecule 1

Background

TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNF superfamily member 15 (TNFSF15). TL1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-alpha and IL-1alpha. TL1A binds with high affinity to death receptor 3 (DR3), now known as TNFRSF25. Depending on the cell context, ligation of DR3 by TL1A can trigger one of two signaling pathways, activation of the transcription factor NF-kB, or activation of caspases and apoptosis.

Publications for TL1A/TNFSF15 (DY1319-05)(4)

Publications using DY1319-05

• Harel, K;Czamanski-Cohen, J;Cohen, M;Lane, RD;Dines, M;Caspi, O;Weihs, KL; Differences in Emotional Awareness Moderate Cytokine-Symptom Associations Among Breast Cancer Survivors Brain, behavior, and immunity 2024-12-12 [PMID: 39674559] (Human)
• Jurickova, I;Dreskin, BW;Angerman, E;Bonkowski, E;Tominaga, K;Iwasawa, K;Braun, T;Takebe, T;Helmrath, MA;Haberman, Y;Wells, JM;Denson, LA; Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohn's Disease bioRxiv : the preprint server for biology 2024-01-30 [PMID: 38352573] (Human)
• T Hisamoto, H Suga, A Yoshizaki-, S Sato, A Yoshizaki Increased Serum Levels of Tumor Necrosis Factor-like Ligand 1A in Atopic Dermatitis International Journal of Molecular Sciences, 2023-01-17;24(3):. 2023-01-17 [PMID: 36768135] (Human)
• B Oriol-Tord, A Olvera, C Duran-Cast, A Llano, B Mothe, M Massanella, J Dalmau, C Ganoza, J Sanchez, ML Calle, B Clotet, J Martinez-P, E Negredo, J Blanco, D Hartigan-O, C Brander, M Ruiz-Riol TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses J Immunol, 2020-11-11;0(0):. 2020-11-11 [PMID: 33177161] (Human)

FAQs for TL1A/TNFSF15 (DY1319-05). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.