Human ST2/IL-33R Quantikine ELISA Kit



Product Details

Reactivity HuSpecies Glossary
Applications ELISA

Order Details

Human ST2/IL-33R Quantikine ELISA Kit Summary

The Quantikine Human ST2/IL-33 R Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human ST2 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human ST2 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human ST2 showed linear curves that were parallel to the standard curves obtained using the Q...uantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring ST2.
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Natural and recombinant human ST2 as well as free ST2 and IL-33 complexed ST2
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DST200.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human ST2/IL-33R Quantikine ELISA Kit

  • DER4
  • DER4ST2growth stimulation-expressed
  • Fit-1
  • IL-1 R4
  • IL1R4
  • IL-1R4
  • IL-1RL1
  • IL-33 R
  • IL33R
  • IL-33R
  • interleukin 1 receptor-like 1
  • interleukin 1 receptor-related protein
  • interleukin-1 receptor-like 1
  • Ly84
  • MGC32623
  • Protein ST2
  • ST2
  • ST2L
  • ST2V
  • T1
  • T1homolog of mouse growth stimulation-expressed


ST2, also known as IL-1 R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor. IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for ST2/IL-33R (DST200)(36)

We have publications tested in 1 confirmed species: Human.

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Showing Publications 1 - 10 of 36. Show All 36 Publications.
Publications using DST200 Applications Species
E Palà, A Bustamante, JL Clúa-Espun, J Acosta, F González-L, SD Santos, D Ribas-Segu, J Ballesta-O, A Penalba, M Giralt, I Lechuga-Du, D Gentille-L, A Pedrote, MÁ Muñoz, J Montaner Blood-biomarkers and devices for atrial fibrillation screening: Lessons learned from the AFRICAT (Atrial Fibrillation Research In CATalonia) study PLoS ONE, 2022;17(8):e0273571. 2022 [PMID: 35998199] (Human) Human
J Luther, AG Vannier, EA Schaefer, RP Goodman The circulating proteomic signature of alcohol-associated liver disease JCI Insight, 2022;7(14):. 2022 [PMID: 35866482] (Human) Human
P Simeone, R Tripaldi, A Michelsen, T Ueland, R Liani, S Ciotti, KI Birkeland, HL Gulseth, A Di Casteln, F Cipollone, P Aukrust, A Consoli, B Halvorsen, F Santilli Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss Cardiovascular Diabetology, 2022;21(1):36. 2022 [PMID: 35277168] (Human) Human
E Mai, J Chan, L Goon, BK Ego, J Bevers, T Wong, M Wong, R Corpuz, H Xi, J Wu, K Schneider, D Seshasayee, M Grimbaldes, G Nakamura, VB Indjeian, M van Looker, KM Loyet, L Comps-Agra Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development Journal of Translational Medicine, 2021;19(1):517. 2021 [PMID: 34930320] (Human) Human
Y Su, Y Sun, Y Tang, H Li, X Wang, X Pan, W Liu, X Zhang, F Zhang, Y Xu, C Yan, SB Ong, D Xu Circulating miR-19b-3p as a Novel Prognostic Biomarker for Acute Heart Failure Journal of the American Heart Association, 2021;10(20):e022304. 2021 [PMID: 34612058] (Human) Human
AM Ambari, B Setianto, A Santoso, B Radi, B Dwiputra, E Susilowati, F Tulrahmi, A Wind, MJM Cramer, P Doevendans Randomised controlled trial into the role of ramipril in fibrosis reduction in rheumatic heart disease: the RamiRHeD trial protocol BMJ Open, 2021;11(9):e048016. 2021 [PMID: 34518254] (Human) Human
Y Yao, L Feng, Y Sun, S Wang, J Sun, B Hu Myocardial fibrosis combined with NT-proBNP improves the accuracy of survival prediction in ADHF patients BMC cardiovascular disorders, 2021;21(1):264. 2021 [PMID: 34049488] (Human) Human
A Cyr, Y Zhong, SE Reis, RA Namas, A Amoscato, B Zuckerbrau, J Sperry, R Zamora, Y Vodovotz, TR Billiar Analysis of the Plasma Metabolome after Trauma, Novel Circulating Sphingolipid Signatures, and In-Hospital Outcomes Journal of the American College of Surgeons, 2021;0(0):. 2021 [PMID: 33453380] (Human) Human
MA Hannappe, L Arnould, A Méloux, B Mouhat, F Bichat, M Zeller, Y Cottin, C Binquet, C Vergely, C Creuzot-Ga, C Guenancia Vascular density with optical coherence tomography angiography and systemic biomarkers in low and high cardiovascular risk patients Sci Rep, 2020;10(1):16718. 2020 [PMID: 33028913] (Human) Human
E Kowalik, A Kwiatek-Wr, A Klisiewicz, A Lutynska, EK Biernacka, M Kowalski, P Hoffman Systemic right ventricle in elderly patients with congenitally corrected transposition of the great arteries: Clinical profile, cardiac biomarkers, and echocardiographic parameters Anatol J Cardiol, 2020;24(2):92-96. 2020 [PMID: 32749250] (Human) Human
Show All 36 Publications.

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Gene Symbol IL1RL1