Human ST2/IL-33R Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human ST2/IL-33R Quantikine ELISA Kit Summary

Background
The Quantikine Human ST2/IL-33 R Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human ST2 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human ST2 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human ST2 showed linear curves that were parallel to the standard curves obtained using the Q...uantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring ST2.
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Specificity
Natural and recombinant human ST2 as well as free ST2 and IL-33 complexed ST2
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
IL1RL1

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DST200.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human ST2/IL-33R Quantikine ELISA Kit

  • DER4
  • DER4ST2growth stimulation-expressed
  • Fit-1
  • IL-1 R4
  • IL1R4
  • IL-1R4
  • IL-1RL1
  • IL-33 R
  • IL33R
  • IL-33R
  • interleukin 1 receptor-like 1
  • interleukin 1 receptor-related protein
  • interleukin-1 receptor-like 1
  • Ly84
  • MGC32623
  • Protein ST2
  • ST2
  • ST2L
  • ST2V
  • T1
  • T1homolog of mouse growth stimulation-expressed

Background

ST2, also known as IL-1 R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor. IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for ST2/IL-33R (DST200)(21)

We have publications tested in 1 confirmed species: Human.


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Human
(21)
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Showing Publications 1 - 10 of 21. Show All 21 Publications.
Publications using DST200 Applications Species
MM Abhyankar, JZ Ma, KW Scully, AJ Nafziger, AL Frisbee, MM Saleh, GR Madden, AR Hays, M Poulter, WA Petri Immune Profiling To Predict Outcome of Clostridioides difficile Infection MBio, 2020;11(3):. 2020 [PMID: 32457246] (Human) Human
FG Scurt, J Menne, S Brandt, A Bernhardt, PR Mertens, H Haller, C Chatzikyrk, Systemic Inflammation Precedes Microalbuminuria in Diabetes Kidney Int Rep, 2019;4(10):1373-1386. 2019 [PMID: 31701047] (Human) Human
CK Wu, MM Su, YF Wu, JJ Hwang, LY Lin Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients J Clin Med, 2018;7(11):. 2018 [PMID: 30413105] (Human) Human
ES Lepojärvi, HV Huikuri, OP Piira, AM Kiviniemi, JA Miettinen, T Kenttä, O Ukkola, JS Perkiömäki, MP Tulppo, MJ Junttila Biomarkers as predictors of sudden cardiac death in coronary artery disease patients with preserved left ventricular function (ARTEMIS study) PLoS ONE, 2018;13(9):e0203363. 2018 [PMID: 30226845] (Human) Human
M Watanabe, K Nakamoto, T Inui, M Sada, K Honda, M Tamura, Y Ogawa, T Yokoyama, T Saraya, D Kurai, H Ishii, H Takizawa Serum sST2 levels predict severe exacerbation of asthma Respir. Res., 2018;19(1):169. 2018 [PMID: 30176857] (Human) Human
ZH Wei, YY Li, SQ Huang, ZQ Tan Genetic variants in IL-33/ST2 pathway with the susceptibility to hepatocellular carcinoma in a Chinese population Cytokine, 2018;0(0):. 2018 [PMID: 29656959] (Human) Human
D Binas, H Daniel, A Richter, V Ruppert, KD Schlüter, B Schieffer, S Pankuweit The prognostic value of sST2 and galectin-3 considering different aetiologies in non-ischaemic heart failure Open Heart, 2018;5(1):e000750. 2018 [PMID: 29531765] (Human) Human
FN Dijk, C Xu, E Melén, AE Carsin, A Kumar, IM Nolte, O Gruzieva, G Pershagen, NS Grotenboer, OEM Savenije, JM Antó, I Lavi, C Dobaño, J Bousquet, P van der Vl, RJP van der Va, JC de Jongste, MC Nawijn, S Guerra, DS Postma, GH Koppelman Genetic regulation ofIL1RL1methylation and IL1RL1-a protein levels in asthma Eur. Respir. J., 2018;51(3):. 2018 [PMID: 29519908] (Human) Human
JE Miller, SP Monsanto, SH Ahn, K Khalaj, AT Fazleabas, SL Young, BA Lessey, M Koti, C Tayade Interleukin-33 modulates inflammation in endometriosis Sci Rep, 2017;7(1):17903. 2017 [PMID: 29263351] (Human) Human
SJ Rotz, CE Dandoy, MD Taylor, S Jodele, JL Jefferies, A Lane, JA El-Bietar, AW Powell, SM Davies, TD Ryan Long-term systolic function in children and young adults after hematopoietic stem cell transplant Bone Marrow Transplant., 2017;0(0):. 2017 [PMID: 28714947] (Human) Human
Show All 21 Publications.

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FAQs for ST2/IL-33R (DST200). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.
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Bioinformatics

Gene Symbol IL1RL1