Human Midkine DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Midkine DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: MDK

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Midkine DuoSet ELISA, 15 Plate

• Amphiregulin-associated protein
• ARAP
• MDK
• MEK
• Midgestation and kidney protein
• midkine (neurite growth-promoting factor 2)
• Midkine
• MK1
• MKARAP
• NEGF2
• NEGF2FLJ27379
• Neurite outgrowth-promoting factor 2
• Neurite outgrowth-promoting protein

Background

Midkine (MK) is a member of a family of neurotrophic and developmentally-regulated heparin-binding molecules that currently consists of midkine, pleiotrophin/PTN and avian RI-HB. Across species, MK shows 87% amino acid identity between the human and mouse proteins. Between family members, human MK is approximately 50% identical to human PTN.

Publications for Midkine (DY258)(6)

Publications using DY258

• Xu, Y;Li, W;Shi, J;Guo, Y; Midkine promotes PDGF-BB-induced proliferation, migration, and glycolysis of airway smooth muscle cells via the PI3K Akt pathway Physiological reports 2025-09-01 [PMID: 40969143] (Human)
• B Sun, C Hu, Z Yang, X Zhang, L Zhao, J Xiong, J Ma, L Chen, H Qian, X Luo, L Shi, J Li, X Cheng, Z Yin Midkine promotes hepatocellular carcinoma metastasis by elevating anoikis resistance of circulating tumor cells Oncotarget, 2017-05-16;8(20):32523-32535. 2017-05-16 [PMID: 28430645] (Human)
• Q Jia, Z Meng, K Xu, X He, J Tan, G Zhang, X Li, N Liu, T Hu, P Zhou, S Wang, A Upadhyaya, X Liu, H Wang, C Zhang Serum midkine as a surrogate biomarker for metastatic prediction in differentiated thyroid cancer patients with positive thyroglobulin antibody Sci Rep, 2017-02-27;7(0):43516. 2017-02-27 [PMID: 28240744] (Human)
• D Vu Van, U Heberling, MP Wirth, S Fuessel Validation of the diagnostic utility of urinary midkine for the detection of bladder cancer Oncol Lett, 2016-08-23;12(5):3143-3152. 2016-08-23 [PMID: 27899974] (Human)
• Fan N, Sun H, Wang Y, Zhang L, Xia Z, Peng L, Hou Y, Shen W, Liu R, Peng Y Midkine, a potential link between obesity and insulin resistance. PLoS ONE, 2014-02-07;9(2):e88299. 2014-02-07 [PMID: 24516630] (Human)
• ERbeta-mediated estradiol enhances epithelial mesenchymal transition of lung adenocarcinoma through increasing transcription of midkine. Mol. Endocrinol., 2012-06-05;26(8):1304-15. 2012-06-05 [PMID: 22669742] (Human)

FAQs for Midkine (DY258). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: MDK