Human Mer DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Mer DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: MERTK

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Mer DuoSet ELISA, 15 Plate

• c-Eyk
• c-mer proto-oncogene tyrosine kinase
• C-mer
• EC 2.7.10
• EC 2.7.10.1
• MER receptor tyrosine kinase
• Mer
• MerTK
• MGC133349
• Receptor tyrosine kinase MerTK
• RP38Proto-oncogene c-Mer
• STK kinase
• tyrosine-protein kinase Mer

Background

Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse orthologs of chicken c-Eyk) constitute the TAM receptor tyrosine kinase subfamily. This RTK subfamily is characterized by an extracellular domain that consists of two Ig-like motifs and two fibronectin type III motifs. These receptors bind the vitamin K-dependent protein Growth Arrest Specific Gene 6 (Gas6). Receptor activation leads to cell proliferation, migration, or the prevention of apoptosis. Cellular signaling through this family of RTKs is involved in hematopoiesis, embryonic development, tumorigenesis, and spermatogenesis.

Publications for Mer (DY6488)(7)

Publications using DY6488

• Xiong, Y;Wang, B;Jiao, J;Tang, M;Li, K;Jiang, R;Huang, W; Expression and clinical association of MFG-E8 and TAM receptors in diabetic patients with different stages of microvascular complication: An experimental study Medicine 2023-11-03 [PMID: 37933040] (Human)
• D Apostolo, D D'Onghia, S Tonello, R Minisini, A Baricich, C Gramaglia, F Patrucco, P Zeppegno, A Acquaviva, PE Balbo, LM Castello, G Cappellano, A Chiocchett, C Gerevini, M Giordano, F Laaguid, M Manfredi, D Raineri, C Rigamonti, R Rolla, V Romano, M Confalonie, P Savoia, E Zavattaro, M Pirisi, B Ruaro, PP Sainaghi, M Bellan, No-More CO Decreased Gas6 and sAxl Plasma Levels Are Associated with Hair Loss in COVID-19 Survivors International Journal of Molecular Sciences, 2023-03-26;24(7):. 2023-03-26 [PMID: 37047229] (Human)
• S Tonello, M Rizzi, E Matino, M Costanzo, GF Casciaro, A Croce, E Rizzi, E Zecca, A Pedrinelli, V Vassia, R Landi, M Bellan, LM Castello, R Minisini, VR Mallela, D D'Onghia, GC Avanzi, M Pirisi, D Lilleri, PP Sainaghi Baseline Plasma Gas6 Protein Elevation Predicts Adverse Outcomes in Hospitalized COVID-19 Patients Disease Markers, 2022-04-29;2022(0):1568352. 2022-04-29 [PMID: 35531477] (Human)
• J Vullings, JP Vago, CEJ Waterborg, RM Thurlings, MI Koenders, PLEM van Lent, PM van der Kr, FA Amaral, FAJ van de Loo Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis J Immunol Res, 2020-09-11;2020(0):9690832. 2020-09-11 [PMID: 32964059] (Human)
• SJ Wang, R Li, TSC Ng, G Luthria, MJ Oudin, M Prytyskach, RH Kohler, R Weissleder, DA Lauffenbur, MA Miller Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy Sci Adv, 2020-05-22;6(21):eaaz8521. 2020-05-22 [PMID: 32494745] (Human)
• M Bellan, A Dimagli, C Piccinino, A Giubertoni, A Ianniello, F Grimoldi, M Sguazzotti, A Nerviani, M Barini, A Carriero, C Smirne, ME Burlone, C Rigamonti, R Minisini, L Salmi, MN Barbaglia, LM Castello, D Sola, P Marino, GC Avanzi, M Pirisi, PP Sainaghi Role of Gas6 and TAM Receptors in the Identification of Cardiopulmonary Involvement in Systemic Sclerosis and Scleroderma Spectrum Disorders Dis. Markers, 2020-05-12;2020(0):2696173. 2020-05-12 [PMID: 32454903] (Human)
• A Tutusaus, E de Gregori, B Cucarull, H Cristóbal, C Aresté, I Graupera, M Coll, A Colell, G Gausdal, JB Lorens, P García de, A Morales, M Marí A FUNCTIONAL ROLE OF GAS6/TAM IN NON-ALCOHOLIC STEATOHEPATITIS PROGRESSION IMPLICATES AXL AS THERAPEUTIC TARGET Cell Mol Gastroenterol Hepatol, 2019-11-02;0(0):. 2019-11-02 [PMID: 31689560] (Human)

FAQs for Mer (DY6488). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: MERTK