Applications: WB, ELISA, PA
Applications: RNAi, RNAi SP
MerTK (c-mer, Nyk, Eyk) is a tyrosine kinase that belongs to a family of transmembrane receptors (1). MerTk has been implicated in reversible cell growth arrest, survival, proliferation and cell adhesion. Growth arrest specific protein 6 (Gas6) is an activating ligand for MerTK (2-3). MerTK is required for clearance of apoptotic cells by mononuclear phagocytes in mice; with its absence resulting in progressive lupus like autoimmunity (4). Defects in MERTK are a cause of retinitis pigmentosa (RP) (5).
|Product By Gene ID
- EC 2.7.10
- tyrosine-protein kinase Mer
- EC 126.96.36.199
- STK kinase
- MER receptor tyrosine kinase
- Receptor tyrosine kinase MerTK
- RP38Proto-oncogene c-Mer
- c-mer proto-oncogene tyrosine kinase
Bioinformatics Tool for Mer
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