Mer Products

Antibodies
Mer Antibody [Unconjugated]
Mer Antibody [Unconjugated]
AF591
Species: Mu
Applications: Flow, IHC, CyTOF-ready, Dual ISH-IHC
Host: Goat Polyclonal
Mer Antibody [Unconjugated]
Mer Antibody [Unconjugated]
AF891
Species: Hu
Applications: WB, Flow, CyTOF-ready, KO
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
ELISA Kits
Human Total Mer DuoSet IC ELI ...
Human Total Mer DuoSet IC ELISA, 2...
DYC891-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Mouse Mer DuoSet ELISA, 15 Pl ...
Mouse Mer DuoSet ELISA, 15 Plate
DY591
Species: Mu
Applications: ELISA
Human Mer DuoSet ELISA, 15 Pl ...
Human Mer DuoSet ELISA, 15 Plate
DY6488
Species: Hu
Applications: ELISA
Lysates
Mer Overexpression Lysate
Mer Overexpression Lysate
NBP2-07636
Species: Hu
Applications: WB
Proteins
Recombinant Human Mer Fc Chim ...
Recombinant Human Mer Fc Chimera P...
891-MR
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Recombinant Human Mer Protein ...
Recombinant Human Mer Protein
P5596
Species: Hu
Applications: Func, PAGE
Mer Recombinant Protein Antig ...
Mer Recombinant Protein Antigen
NBP2-58025PEP
Species: Hu
Applications: AC

Description

MerTK (c-mer, Nyk, Eyk) is a tyrosine kinase that belongs to a family of transmembrane receptors (1). MerTk has been implicated in reversible cell growth arrest, survival, proliferation and cell adhesion. Growth arrest specific protein 6 (Gas6) is an activating ligand for MerTK (2-3). MerTK is required for clearance of apoptotic cells by mononuclear phagocytes in mice; with its absence resulting in progressive lupus like autoimmunity (4). Defects in MERTK are a cause of retinitis pigmentosa (RP) (5).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Mouse
Product By Gene ID 10461
Alternate Names
  • EC 2.7.10
  • mer
  • tyrosine-protein kinase Mer
  • EC 2.7.10.1
  • STK kinase
  • MER
  • MER receptor tyrosine kinase
  • Receptor tyrosine kinase MerTK
  • c-mer
  • RP38Proto-oncogene c-Mer
  • MGC133349
  • c-mer proto-oncogene tyrosine kinase

Research Areas for Mer

Find related products by research area and learn more about each of the different research areas below.

Cancer
Phospho-Specific
Protein Kinase
Signal Transduction
Vision

Bioinformatics Tool for Mer

Discover related pathways, diseases and genes to Mer. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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