Human IL-32 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-32 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL32

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-32 DuoSet ELISA, 5 Plate

• IL32
• IL-32
• IL-32alpha
• IL-32beta
• interleukin 32
• interleukin-32 theta
• interleukin-32
• natural killer cell transcript 4
• Natural killer cells protein 4
• NK4
• NK4IL-32delta
• TAIF
• TAIFa
• TAIFb
• TAIFc
• TAIFd
• TAIFIL-32gamma
• Tumor necrosis factor alpha-inducing factor

Background

IL-32 alpha is the shortest and most abundant of four potential splice variants of the proinflammatory cytokine IL-32 (previously called NK4) with a predicted unmodified size of 15 kDa. Potential modifications include myristoylation and N-glycosylation. Transfected IL-32 alpha was more likely to be cell-associated as compared to IL-32 beta, suggesting an intracellular function. IL-32 is induced by mitogens in peripheral lymphocytes, by IFN-gamma in epithelial cells, or by IL-12 with IL-18 in NK cells and in turn induces cytokine expression. No ortholog has been found in mouse.

Publications for IL-32 (DY3040-05)(10)

Publications using DY3040-05

• Mester, P;Utrata, A;Schmidtner, N;Birner, C;Schmid, S;Müller, M;Pavel, V;Buechler, C; Lower Plasma IL-32 Levels Linked to Better Survival in Sepsis Biomedicines 2025-03-19 [PMID: 40149726] (Human)
• Soussi, S;Maione, AS;Lefèvre, L;Pizzinat, N;Iacovoni, J;Gonzalez-Fuentes, I;Cussac, D;Iengo, L;Santin, Y;Tundo, F;Tondo, C;Pompilio, G;Parini, A;Douin-Echinard, V;Sommariva, E; Analysis of effector/memory regulatory T cells from arrhythmogenic cardiomyopathy patients identified IL-32 as a novel player in ACM pathogenesis Cell death & disease 2025-02-11 [PMID: 39934117] (Human)
• M Tomasi, A Cherubini, S Pelusi, S Margarita, C Bianco, F Malvestiti, L Miano, S Romeo, D Prati, L Valenti Circulating Interlukin-32 and Altered Blood Pressure Control in Individuals with Metabolic Dysfunction International Journal of Molecular Sciences, 2023-04-18;24(8):. 2023-04-18 [PMID: 37108628] (Human)
• H Chen, W Yang, X Xue, Y Li, Z Jin, Z Ji Integrated Analysis Revealed an Inflammatory Cancer-Associated Fibroblast-Based Subtypes with Promising Implications in Predicting the Prognosis and Immunotherapeutic Response of Bladder Cancer Patients International Journal of Molecular Sciences, 2022-12-15;23(24):. 2022-12-15 [PMID: 36555612] (Human)
• YLL Braga, JRC Neto, AWF Costa, MVT Silva, MV Silva, MRN Celes, MAP Oliveira, LAB Joosten, F Ribeiro-Di, RS Gomes, JR Machado Interleukin-32gamma in the Control of Acute Experimental Chagas Disease Journal of Immunology Research, 2022-01-20;2022(0):7070301. 2022-01-20 [PMID: 35097133] (Mouse)
• JC Dos Santos, AM Barroso de, MV Teodoro Si, B Cirovic, LCJ de Bree, MSMA Damen, SJCFM Moorlag, RS Gomes, MM Helsen, M Oosting, ST Keating, A Schlitzer, MG Netea, F Ribeiro-Di, LAB Joosten β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32 Cell Rep, 2019-09-03;28(10):2659-2672.e6. 2019-09-03 [PMID: 31484076] (Human, Transgenic Mouse)
• R Fadaei, N Bagheri, E Heidarian, A Nouri, Z Hesari, N Moradi, A Ahmadi, R Ahmadi Serum levels of IL-32 in patients with type 2 diabetes mellitus and its relationship with TNF-α and IL-6 Cytokine, 2019-08-31;125(0):154832. 2019-08-31 [PMID: 31479874] (Human)
• P Comella-De, R Abellana, R Villar-Her, MD Jean Coute, B Sallés Min, L Canales Al, M Narcisse, J Gautier, C Ascaso, I Latorre, J Dominguez, TM Perez-Porc A Model Based on the Combination of IFN-gamma, IP-10, Ferritin and 25-Hydroxyvitamin D for Discriminating Latent From Active Tuberculosis in Children Front Microbiol, 2019-08-14;10(0):1855. 2019-08-14 [PMID: 31474956] (Human)
• Muhammad Zahoor, Marita Westhrin, Kristin Roseth Aass, Siv Helen Moen, Kristine Misund, Katarzyna Maria Psonka-Antonczyk et al. Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss Blood Advances 2017-12-26 [PMID: 29296919] (Human)
• H Sato, S Muraoka, N Kusunoki, S Masuoka, S Yamada, H Ogasawara, T Imai, Y Akasaka, N Tochigi, H Takahashi, K Tsuchiya, S Kawai, T Nanki Resistin upregulates chemokine production by fibroblast-like synoviocytes from patients with rheumatoid arthritis Arthritis Res. Ther., 2017-12-01;19(1):263. 2017-12-01 [PMID: 29191223] (Human)

FAQs for IL-32 (DY3040-05). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: IL32