Human GM-CSF Quantikine ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

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Catalog# & Conjugate Size Price

Human GM-CSF Quantikine ELISA Kit Summary

Background
The Quantikine Human GM-CSF Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure GM-CSF levels in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human GM-CSF and antibodies raised against the recombinant factor. It has been shown to quantitate recombinant human GM-CSF accurately. Results obtained using natural human GM-CSF sho...wed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural GM-CSF.
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Specificity
Natural and recombinant human GM-CSF
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CSF2

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DGM00 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human GM-CSF Quantikine ELISA Kit

  • colony stimulating factor 2 (granulocyte-macrophage)
  • Colony-stimulating factor
  • CSF
  • CSF2
  • CSF-2
  • GMCSF
  • GM-CSF
  • GMCSFgranulocyte-macrophage colony-stimulating factor
  • granulocyte-macrophage colony stimulating factor
  • MGC131935
  • MGC138897
  • Molgramostim
  • molgramostin
  • Sargramostim

Background

GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the inflammatory activation of dendritic cells, microglia, alveolar macrophages, and eosinophils. In addition, it cooperates with G-CSF in promoting tumor cell proliferation and invasion. GM-CSF signals through a receptor complex composed of GM-CSF R alpha and the Common beta Chain (beta c) with Syndecan-2 as a potential co-receptor. The beta c subunit is shared by the receptor complexes for IL-3 and IL-5.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for GM-CSF (DGM00)(46)

We have publications tested in 3 confirmed species: Human, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque), Rabbit.

We have publications tested in 1 application: ELISA Capture.


Filter By Application
ELISA Capture
(1)
All Applications
Filter By Species
Human
(42)
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
(1)
Rabbit
(1)
All Species
Showing Publications 1 - 10 of 46. Show All 46 Publications.
Publications using DGM00 Applications Species
T Sun, M Ju, X Dai, H Dong, W Gu, Y Gao, R Fu, X Liu, Y Huang, W Liu, Y Chi, W Wang, H Li, Y Zhou, L Shi, R Yang, L Zhang Multilevel defects in the hematopoietic niche in essential thrombocythemia Haematologica, 2019;0(0):. 2019 [PMID: 31289202] (Human) Human
D Hao, X Wen, L Liu, L Wang, X Zhou, Y Li, X Zeng, G He, X Jiang Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy Cell Death Dis, 2019;10(1):19. 2019 [PMID: 30622245] (Human) Human
K Huang, L Ran, W Wang, R Zhou, X Cai, R Li, Y Li, C Zhou, W He, R Wang Glucocorticoid insensitivity by staphylococcal enterotoxin B in keratinocytes of allergic dermatitis is associated with impaired nuclear translocation of the Glucocorticoid Receptor ? J. Dermatol. Sci., 2018;92(3):272-280. 2018 [PMID: 30522881] (Human) Human
V Kemp, DJM van den Wo, MGM Camps, T van Hall, P Kinderman, N Pronk-van, RC Hoeben Arming oncolytic reovirus with GM-CSF gene to enhance immunity Cancer Gene Ther., 2018;0(0):. 2018 [PMID: 30467340]
G Jordakieva, I Grabovac, E Valic, KE Schmidt, A Graff, A Schuster, K Hoffmann-S, C Oberhuber, O Scheiner, A Goll, J Godnic-Cva Occupational exposure to ultrafine particles in police officers: no evidence for adverse respiratory effects J Occup Med Toxicol, 2018;13(0):5. 2018 [PMID: 29434649] (ELISA Capture, Human) ELISA Capture Human
F Reggiani, V Labanca, P Mancuso, C Rabascio, G Talarico, S Orecchioni, A Manconi, F Bertolini Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression Cancer Res., 2017;0(0):. 2017 [PMID: 28754674] (Human) Human
YH Sun, L He, MY Yan, RQ Zhao, B Li, F Wang, Y Yang, HP Yu Overexpression of GLP-1 receptors suppresses proliferation and cytokine release by airway smooth muscle cells of patients with chronic obstructive pulmonary disease via activation of ABCA1 Mol Med Rep, 2017;0(0):. 2017 [PMID: 28560433]
Ingrid C Weel Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia PLoS ONE, 2016;11(6):e0157584. 2016 [PMID: 27315098] (Human) Human
Pundir P, MacDonald C, Kulka M The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production. J Immunol, 2015;195(6):2774-87. 2015 [PMID: 26283482] (Human) Human
Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, Kanda T, Ransohoff R Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli? PLoS ONE, 2015;10(7):e0133392. 2015 [PMID: 26197437] (Human) Human
Show All 46 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for GM-CSF (DGM00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DGM00
HRP DGM00
HRP DGM00

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Bioinformatics

Gene Symbol CSF2