Human Erythropoietin R DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Erythropoietin R DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: EPOR

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Erythropoietin R DuoSet ELISA, 15 Plate

• EpoR
• EPO-R
• Erythropoietin R
• erythropoietin receptor
• MGC138358

Background

Erythropoietin (Epo) is a 30-kDa, heavily glycosylated protein produced primarily by the kidney. It is the principal factor that regulates erythropoiesis. The production of Epo by kidney cells is increased in response to hypoxia or anemia. The cDNAs for Epo have been cloned from many species. The mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level.

The biological effects of Epo are mediated by the Erythropoietin receptor (Epo R). At the protein sequence level, the human Epo R is approximately 83% identical to the mouse protein. As a result of alternative splicing of the Epo R gene, cDNA clones encoding truncated soluble forms of Epo R have been found. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

Publications for Erythropoietin R (DY307)(3)

Publications using DY307

• Colleen Glyde Julian Erythropoietin and Soluble Erythropoietin Receptor: A Role for Maternal Vascular Adaptation to High Altitude Pregnancy J. Clin. Endocrinol. Metab., 2017-01-01;0(0):jc20161767. 2017-01-01 [PMID: 27809650] (Human)
• Inrig JK, Bryskin SK, Patel UD, Arcasoy M, Szczech LA Association between high-dose erythropoiesis-stimulating agents, inflammatory biomarkers, and soluble erythropoietin receptors. BMC Nephrol, 2011-12-12;12(0):67. 2011-12-12 [PMID: 22152013] (Human)
• Khankin EV, Mutter WP, Tamez H Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease. PLoS ONE, 2010-02-16;5(2):e9246. 2010-02-16 [PMID: 20169072] (Human)

FAQs for Erythropoietin R (DY307). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: EPOR