Human CXCL13/BLC/BCA-1 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human CXCL13/BLC/BCA-1 Quantikine ELISA Kit Summary

Background
The Quantikine Human BLC/BCA-1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human BLC/BCA-1 in cell culture supernates, serum, plasma, and saliva. It contains E. coli-expressed recombinant human BLC/BCA-1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human BLC/BCA-1 showed linear curves that were parallel to the... standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring BLC/BCA-1.
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Specificity
Natural and recombinant human BLC/BCA-1
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CXCL13

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DCX130.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CXCL13/BLC/BCA-1 Quantikine ELISA Kit

  • ANGIE
  • ANGIE2
  • B cell-attracting chemokine 1
  • B lymphocyte chemoattractant
  • BCA1
  • BCA-1
  • BCA1B-cell chemoattractant
  • BCA-1CXC chemokine BLC
  • B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)
  • BLC
  • BLCSmall-inducible cytokine B13
  • BLR1L
  • B-lymphocyte chemoattractant
  • chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)
  • chemokine (C-X-C motif) ligand 13
  • C-X-C motif chemokine 13
  • CXCL13
  • SCYB13
  • SCYB13B-cell-attracting chemokine 1
  • small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cellchemoattractant)

Background

CXCL13/BLC/BCA-1 is a constitutively expressed chemokine that plays an important role in B and T cell homing. It is expressed by salivary gland epithelium, dendritic cells, osteoclasts, and peritoneal macrophages. It can form homodimers or heterodimers with FGF basic, and it signals through CXCR3 or CXCR5. CXCL13 induces the migration of naïve B cells and a subset of memory T cells to lymphoid tissue. It also promotes B1 cell migration into the omentum and peritoneum. In the fetus, CXCL13 attracts CD4+ CD3- IL-7 R alpha+ hematopoietic cells to sites of future Peyer’s patch development.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CXCL13/BLC/BCA-1 (DCX130)(36)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Filter By Species
Human
(36)
All Species
Showing Publications 1 - 10 of 36. Show All 36 Publications.
Publications using DCX130 Applications Species
F Saberi Hos, PM Kolijn, D Casabonne, A Nieters, M Solans, S Naudin, P Ferrari, JD Mckay, E Weiderpass, V Perduca, C Besson, FR Mancini, G Masala, V Krogh, F Ricceri, JM Huerta, D Petrova, N Sala, A Trichopoul, A Karakatsan, C La Vecchia, R Kaaks, F Canzian, D Aune, H Boeing, MB Schulze, A Perez-Corn, AW Langerak, VHJ van der Ve, R Vermeulen Mediating effect of soluble B-cell activation immune markers on the association between anthropometric and lifestyle factors and lymphoma development Sci Rep, 2020;10(1):13814. 2020 [PMID: 32796953] (Human) Human
AM Globig, NP Sommer, K Wild, J Schardey, K Zoldan, AK Thomann, LA Schulte, R Schreiner, W Reindl, J Klaus, CM Schempp, M Hofmann, R Thimme, T Boettler, P Hasselblat Ustekinumab inhibits T follicular helper cell differentiation in patients with Crohn's disease Cell Mol Gastroenterol Hepatol, 2020;0(0):. 2020 [PMID: 32679193] (Human) Human
DM Muema, NA Akilimali, OC Ndumnego, SS Rasehlo, R Durgiah, DBA Ojwach, N Ismail, M Dong, A Moodley, KL Dong, ZM Ndhlovu, JM Mabuka, BD Walker, JK Mann, T Ndung'u Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection BMC Med, 2020;18(1):81. 2020 [PMID: 32209092] (Human) Human
S Miyajima, K Shigehara, R Kamekura, H Takaki, H Yabe, I Ikegami, Y Asai, H Nishikiori, H Chiba, E Uno, H Takahashi, S Ichimiya Activated circulating T follicular helper cells and skewing of T follicular helper 2�cells are down-regulated by treatment including an inhaled corticosteroid in patients with allergic asthma Allergol Int, 2019;0(0):. 2019 [PMID: 31648923] (Human) Human
A Morou, E Brunet-Rat, M Dubé, R Charlebois, E Mercier, S Darko, N Brassard, K Nganou-Mak, S Arumugam, G Gendron-Le, L Yang, J Niessl, AE Baxter, JM Billingsle, PA Rajakumar, F Lefebvre, RP Johnson, C Tremblay, JP Routy, RT Wyatt, A Finzi, DC Douek, DE Kaufmann Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease Nat. Immunol., 2019;20(8):1059-1070. 2019 [PMID: 31308541] (Human) Human
A Ardain, R Domingo-Go, S Das, SW Kazer, NC Howard, A Singh, M Ahmed, S Nhamoyebon, J Rangel-Mor, P Ogongo, L Lu, D Ramsuran, M de la Luz, T K Ulland, M Darby, E Park, F Karim, L Melocchi, R Madansein, KJ Dullabh, M Dunlap, N Marin-Agud, T Ebihara, T Ndung'u, D Kaushal, AS Pym, JK Kolls, A Steyn, J Zúñiga, W Horsnell, WM Yokoyama, AK Shalek, HN Kløverpris, M Colonna, A Leslie, SA Khader Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis Nature, 2019;570(7762):528-532. 2019 [PMID: 31168092] (Human) Human
EJ Im, CH Lee, PG Moon, GG Rangaswamy, B Lee, JM Lee, JC Lee, JG Jee, JS Bae, TK Kwon, KW Kang, MS Jeong, JE Lee, HS Jung, HJ Ro, S Jun, W Kang, SY Seo, YE Cho, BJ Song, MC Baek Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Nat Commun, 2019;10(1):1387. 2019 [PMID: 30918259] (Human) Human
SI Richardson, AW Chung, H Natarajan, B Mabvakure, NN Mkhize, N Garrett, S Abdool Kar, PL Moore, ME Ackerman, G Alter, L Morris HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies PLoS Pathog., 2018;14(4):e1006987. 2018 [PMID: 29630668] (Human) Human
A Pietikäine, J Oksi, J Hytönen Point-of-care testing for CXCL13 in Lyme neuroborreliosis Diagn. Microbiol. Infect. Dis., 2018;0(0):. 2018 [PMID: 29567125] (Human) Human
RM Paris, LG Milagres, E Moysi, JF Okulicz, BK Agan, A Ganesan, C Petrovas, RA Koup Lower Baseline Germinal Center Activity and Preserved Th1 Immunity Are Associated With Hepatitis B Vaccine Response in Treated HIV Infection Pathog Immun, 2017;2(1):66-88. 2017 [PMID: 28580437] (Human) Human
Show All 36 Publications.

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Product General Protocols

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FAQs for CXCL13/BLC/BCA-1 (DCX130). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DCX130

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Bioinformatics

Gene Symbol CXCL13