Human CCL3/MIP-1 alpha Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human CCL3/MIP-1 alpha Quantikine ELISA Kit Summary

• Background: The Quantikine Human MIP-1 alpha Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure MIP-1 alpha levels in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human MIP-1 alpha and antibodies raised against the recombinant protein. Results obtained for naturally occurring human MIP-1 alpha showed linear curves that were parallel t...o the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural human MIP-1 alpha.
  Show More
• Specificity: Natural and recombinant human MIP-1 alpha
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CCL3

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL3/MIP-1 alpha Quantikine ELISA Kit

• C-C motif chemokine 3
• MIP1-(a)
• AI323804
• CCL3
• chemokine (C-C motif) ligand 3
• G0S19-1
• LD78a
• LD78alpha
• MIP1 alpha
• MIP-1 alpha
• MIP1A
• MIP-1alpha
• MIP1-alpha
• PAT 464.1
• SCYA3
• SIS-beta

Background

MIP-1 alpha (macrophage inflammatory protein 1 alpha) is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils.

The two human MIP-1 alpha genes arise by duplication/mutation. They code for MIP-1 alpha isoforms CCL3/LD78a and CCL3L1/LD78b, which share 94% amino acid sequence homology. Whereas the human CCL3/LD78a is a single-copy gene, the human CCL3L1/LD78b gene copy number varies within the population. Human CCL3L1/LD78b binds and signals through chemokine receptors CCR1, CCR5. When compared to CCL3/LD78a, CCL3L1/LD78b has higher binding affinity to CCR5, which also functions as a coreceptor for HIV-1 entry. The copy number of CCL3L1 is one of several genetic determinants of HIV-1 susceptibility.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL3/MIP-1 alpha (DMA00)(63)

Publications using DMA00

• Kido, R;Hiroshima, Y;Kido, JI;Bando, M;Yoshida, K;Inagaki, Y;Yumoto, H; Lipocalin 2 inhibits the expressions of interleukin-8 and macrophage inflammatory protein-1? in human neutrophil-like cells Journal of oral biosciences 2025-01-30 [PMID: 39892784] (Human)
• Polis, B;Zeman, K;Zakrzewski, K;Fabijan, A;Nowos?awska, E; Peripheral white blood cell patterns in children with hydrocephalus as a response to ventriculo-peritoneal shunt infection PloS one 2024-08-09 [PMID: 39121090] (Human)
• Scovino, AM;Dahab, EC;Diniz-Lima, I;de Senna Silveira, E;Barroso, SPC;Cardoso, KM;Nico, D;Makhoul, GJ;da Silva-Junior, EB;Freire-de-Lima, CG;Freire-de-Lima, L;Fonseca, LMD;Valente, N;Nacife, V;Machado, A;Araújo, M;Vieira, GF;Pauvolid-Corrêa, A;Siqueira, M;Morrot, A; A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants Microorganisms 2024-04-02 [PMID: 38674664] (Human)
• T Tsai, M Alwees, MA Asaad, J Theile, V Kakkassery, HB Dick, T Schultz, SC Joachim Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy PLoS ONE, 2023-01-20;18(1):e0280488. 2023-01-20 [PMID: 36662891] (Human)
• E Terpos, I Ntanasis-S, E Kastritis, E Hatjiharis, E Katodritou, E Eleutherak, E Verrou, M Gavriatopo, A Leonidakis, K Manousou, S Delimpasi, P Malandraki, MC Kyrtsonis, M Papaioanno, A Symeonidis, MA Dimopoulos Daratumumab Improves Bone Turnover in Relapsed/Refractory Multiple Myeloma; Phase 2 Study "REBUILD" Oncogene, 2022-06-02;14(11):. 2022-06-02 [PMID: 35681747] (Human)
• Z Liu, J Liu, T Zhang, L Li, S Zhang, H Jia, Y Xia, M Shi, J Zhang, S Yue, X Chen, J Yu Distinct BTK inhibitors differentially induce apoptosis but similarly suppress chemotaxis and lipid accumulation in mantle cell lymphoma BMC Cancer, 2021-06-26;21(1):732. 2021-06-26 [PMID: 34174847] (Human)
• ML Mannakanda, MA Kamran, SE Udeabor, MS Hameed, M Ajmal, I Alshahrani Effect of ultrasonic scaling with adjunctive photodynamic therapy in the treatment of gingival inflammation among diabetic patients undergoing fixed orthodontic treatment Photodiagnosis and photodynamic therapy, 2021-05-27;0(0):102360. 2021-05-27 [PMID: 34052421] (Human)
• E Pandolfi, N Panera, A Alisi, E Carloni, L Russo, I Campagna, C Rizzo, C Concato, G Linardos, L Piccioni, S Jackson, A Villani, F Midulla, AE Tozzi Cytokine expression patterns in hospitalized children with Bordetella pertussis, Rhinovirus or co-infection Scientific Reports, 2021-05-26;11(1):10948. 2021-05-26 [PMID: 34040002] (Human)
• L Avila, ML Neves, AR Abreu, CR Fiuza, L Fukusawa, N Meziat-Fil, AR Soares San Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial Journal of bodywork and movement therapies, 2020-09-14;26(0):428-434. 2020-09-14 [PMID: 33992278] (Human)
• E Terpos, I Ntanasis-S, E Katodritou, MC Kyrtsonis, V Douka, E Spanoudaki, A Papatheodo, E Eleutherak, N Kanellias, M Gavriatopo, P Makras, E Kastritis, MA Dimopoulos Carfilzomib Improves Bone Metabolism in Patients with Advanced Relapsed/Refractory Multiple Myeloma: Results of the CarMMa Study Cancers, 2021-03-12;13(6):. 2021-03-12 [PMID: 33809268] (Human)
• S Sendic, L Mansouri, S Lundberg, A Nopp, SH Jacobson, J Lundahl B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy PLoS ONE, 2021-03-19;16(3):e0248056. 2021-03-19 [PMID: 33740017] (Human)
• M Sivina, L Xiao, E Kim, A Vaca, SS Chen, MJ Keating, A Ferrajoli, Z Estrov, N Jain, WG Wierda, X Huang, N Chiorazzi, JA Burger CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia Leukemia, 2020-10-21;0(0):. 2020-10-21 [PMID: 33087831] (Human)
• T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens An observational study of innate immune responses in patients with acute appendicitis Sci Rep, 2020-10-15;10(1):17352. 2020-10-15 [PMID: 33060696] (Human)
• J Gerosa-Net, PA Monteiro, DS Inoue, BM Antunes, H Batatinha, GP Dorneles, A Peres, JC Rosa-Neto, FS Lira High- and moderate-intensity training modify LPS-induced ex-vivo interleukin-10 production in obese men in response to an acute exercise bout Cytokine, 2020-08-20;136(0):155249. 2020-08-20 [PMID: 32829109] (Human)
• T Kodama, YI Koma, N Arai, A Kido, N Urakawa, M Nishio, M Shigeoka, H Yokozaki CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways Lab. Invest., 2020-05-26;0(0):. 2020-05-26 [PMID: 32457351] (Human)
• L Sadeghi, G Arvidsson, M Merrien, A M Wasik, A Görgens, CIE Smith, B Sander, AP Wright Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells Cancers (Basel), 2020-05-02;12(5):. 2020-05-02 [PMID: 32370190] (Human)
• M Dampmann, A Görgens, M Möllmann, F Murke, U Dührsen, B Giebel, J Dürig CpG stimulation of chronic lymphocytic leukemia cells induces a polarized cell shape and promotes migration in vitro and in vivo PLoS ONE, 2020-02-10;15(2):e0228674. 2020-02-10 [PMID: 32040489] (Human)
• N Aziz, R Detels, JJ Quint, D Gjertson, T Ryner, AW Butch Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests BMC Immunol., 2019-09-14;20(1):33. 2019-09-14 [PMID: 31521107] (Human)
• W Wang, HY Chu, ZM Zhong, X Qi, R Cheng, RJ Qin, J Liang, XF Zhu, MS Zeng, CZ Sun Platelet-secreted CCL3 and its receptor CCR5 promote invasive and migratory abilities of anaplastic thyroid carcinoma cells via MMP-1 Cell. Signal., 2019-07-22;0(0):109363. 2019-07-22 [PMID: 31344439] (Human)
• Wang J, Wu G, Manick B, Hernandez V, Renelt M, Erickson C, Guan J, Singh R, Rollins S, Solorz A, Bi M, Li J, Grabowski D, Dirkx J, Tracy C, Stuart T, Ellinghuysen C, Desmond D, Foster C, Kalabokis V VSIG-3 as a ligand of VISTA inhibits human T-cell function. Immunology, 2018-10-10;156(1):74-85. 2018-10-10 [PMID: 30220083] (Human)
• YL Zhang, B Li, ZH Zhou A cross-sectional study: serum CCL3/MIP-1? levels may reflect lumbar intervertebral disk degeneration in Han Chinese people J Pain Res, 2018-03-05;11(0):497-503. 2018-03-05 [PMID: 29551909] (Human)
• A Stiff, P Trikha, BL Mundy-Boss, EL McMichael, TA Mace, B Benner, K Kendra, A Campbell, S Gautam, D Abood, I Landi, V Hsu, MC Duggan, R Wesolowski, M Old, JH Howard, L Yu, N Stasik, T Olencki, N Muthusamy, S Tridandapa, JC Byrd, MA Caligiuri, WE Carson Nitric Oxide Production by Myeloid Derived Suppressor Cells Plays a Role in Impairing Fc Receptor-Mediated Natural Killer Cell Function Clin. Cancer Res., 2018-01-23;0(0):. 2018-01-23 [PMID: 29363526] (Human)
• N Zhang, G Zhang, N Liu, W Lin, S Ji, M Zheng, K Chen, X Liang, G Li, Y Ma, J Zhu, T Niu, LL Li, J Li, YQ Wei, SY Yang A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models Oncotarget, 2017-12-01;8(67):111495-111507. 2017-12-01 [PMID: 29340070] (Human)
• Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia J Immunol, 2016-08-17;0(0):. 2016-08-17 [PMID: 27534555] (Human)
• Balakrishnan K, Peluso M, Fu M, Rosin N, Burger J, Wierda W, Keating M, Faia K, O'Brien S, Kutok J, Gandhi V The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL. Leukemia, 2015-04-28;29(9):1811-22. 2015-04-28 [PMID: 25917267] (Human)
• Hashimoto A, Tanaka T, Itoh Y, Yamagata A, Kitamura N, Tazawa R, Nakagaki K, Nakata K Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitro. Cytokine, 2014-05-09;68(2):118-26. 2014-05-09 [PMID: 24813650] (Human)
• Ponader S, Chen SS, Buggy JJ The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood, 2011-12-16;119(5):1182-9. 2011-12-16 [PMID: 22180443] (Human)
• Johnson TR, McLellan JS, Graham BS Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2. J. Virol., 2011-11-16;86(3):1339-47. 2011-11-16 [PMID: 22090124] (Human)
• Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Lecon V, Lasocki S, Bouadma L, Philip I, Elbim C, Mentre F, Soler P, Crestani B, Dehoux M Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury. Crit. Care Med., 2012-01-01;40(1):21-8. 2012-01-01 [PMID: 21926612] (Human)
• Sivina M, Hartmann E, Kipps TJ, Rassenti L, Krupnik D, Lerner S, LaPushin R, Xiao L, Huang X, Werner L, Neuberg D, Kantarjian H, O'Brien S, Wierda WG, Keating MJ, Rosenwald A, Burger JA CCL3 (MIP-1alpha) plasma levels and the risk for disease progression in chronic lymphocytic leukemia. Blood, 2010-11-29;117(5):1662-9. 2010-11-29 [PMID: 21115978] (Human)
• Su Y, Amiri KI, Horton LW A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets. Clin. Cancer Res., 2009-12-22;16(1):348-57. 2009-12-22 [PMID: 20028756] (Human)
• Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial. AIDS, 2009-05-15;23(8):929-39. 2009-05-15 [PMID: 19425222] (Human)
• Mabilleau G, Sabokbar A Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE, 2009-01-12;4(1):e4173. 2009-01-12 [PMID: 19137064] (Human)
• Olsnes AM, Ryningen A, Ersvaer E, Bruserud Ø In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22. J. Interferon Cytokine Res., 2008-05-01;28(5):297-310. 2008-05-01 [PMID: 18547160] (Human)
• Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B Duffy antigen modifies the chemokine response in human endotoxemia. Crit. Care Med., 2008-01-01;36(1):159-65. 2008-01-01 [PMID: 18007272] (Human)
• Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Proc. Natl. Acad. Sci. U.S.A., 2007-02-05;104(7):2319-24. 2007-02-05 [PMID: 17283337] (Human)
• Pene J, Chevalier S, Preisser L, Venereau E, Guilleux MH, Ghannam S, Moles JP, Danger Y, Ravon E, Lesaux S, Yssel H, Gascan H Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J. Immunol., 2008-06-01;180(0):7423. 2008-06-01 [PMID: 18490742] (Human)
• Le Quement C, Guenon I, Gillon JY, Lagente V, Boichot E MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol., 2008-04-04;294(6):L1076-84. 2008-04-04 [PMID: 18390828] (Human)
• Pokkali S, Das SD, R L Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. Cytokine, 2008-01-28;41(3):307-14. 2008-01-28 [PMID: 18226915] (Human)
• Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, Colombatti A Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions. Int. J. Cancer, 2008-02-15;122(4):769-76. 2008-02-15 [PMID: 17935139] (Human)
• Abonyo BO, Lebby KD, Tonry JH, Ahmad M, Heiman AS Modulation of eotaxin-3 (CCL26) in alveolar type II epithelial cells. Cytokine, 2007-03-09;36(5):237-44. 2007-03-09 [PMID: 17350279] (Human)
• Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, Elias JA IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. J. Immunol., 2007-02-01;178(3):1948-59. 2007-02-01 [PMID: 17237446] (Human)
• Wong CK, Cheung PF, Ip WK, Lam CW Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB. Am. J. Respir. Cell Mol. Biol., 2005-04-28;33(2):186-94. 2005-04-28 [PMID: 15860795] (Human)
• Capelli A, Di Stefano A, Gnemmi I, Donner CF CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis. Eur. Respir. J., 2005-04-01;25(4):701-7. 2005-04-01 [PMID: 15802346] (Human)
• Grygorczuk S, Pancewicz S, Zajkowska J, Kondrusik M, Rwierzbinska R, Hermanowska-Szpakowicz T Concentrations of macrophage inflammatory proteins MIP-1alpha and MIP-1beta and interleukin 8 (il-8) in lyme borreliosis. Infection, 2004-12-01;32(6):350-5. 2004-12-01 [PMID: 15597225] (Human)
• Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, Kannagi M Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. J. Gen. Virol., 2004-09-01;85(0):2603-13. 2004-09-01 [PMID: 15302954] (Human)
• Parameswaran K, Liang H, Fanat A, Watson R, Snider DP, O'Byrne PM Role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in asthma. J. Allergy Clin. Immunol., 2004-07-01;114(1):73-9. 2004-07-01 [PMID: 15241347] (Human)
• Choi ES, Jakubzick C, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia. Am. J. Respir. Crit. Care Med., 2004-06-10;170(5):508-15. 2004-06-10 [PMID: 15191918] (Human)
• Wang CR, Liu MF, Huang YH, Chen HC Up-regulation of XCR1 expression in rheumatoid joints. Rheumatology (Oxford), 2004-02-17;43(5):569-73. 2004-02-17 [PMID: 14970401] (Human)
• Wang CR, Liu MF Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritis. Clin. Exp. Immunol., 2003-05-01;132(2):371-8. 2003-05-01 [PMID: 12699431] (Human)
• Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells. J. Immunol., 2002-10-15;169(8):4172-82. 2002-10-15 [PMID: 12370346] (Human, Primate - Macaca mulatta (Rhesus Macaque))
• Honczarenko M, Le Y, Glodek AM, Silberstein LE CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Blood, 2002-10-01;100(7):2321-9. 2002-10-01 [PMID: 12239139] (Human)
• Ciesielski CJ, Andreakos E, Foxwell BM, Feldmann M TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion. Eur. J. Immunol., 2002-07-01;32(7):2037-45. 2002-07-01 [PMID: 12115625] (Human)
• Milliken D, Scotton C, Raju S, Balkwill F, Wilson J Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites. Clin. Cancer Res., 2002-04-01;8(4):1108-14. 2002-04-01 [PMID: 11948121] (Human)
• Binninger-Schinzel D, 2019, Norley S, Adler HS, Oberg HH, Kurth R Simian immunodeficiency viruses with defective nef genes show increased susceptibility to the noncytotoxic antiviral activity of CD8+ lymphocytes. 2002-03-01;294(1):209-21. 2002-03-01 [PMID: 11886279] (Human)
• Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity, 2001-06-01;14(6):705-14. 2001-06-01 [PMID: 11420041] (Human)
• Loeuillet C, Bernard G, Remy-Martin J, Saas P, Herve P, Douay L, Chalmers D Distinct hematopoietic support by two human stromal cell lines. Exp. Hematol., 2001-06-01;29(6):736-45. 2001-06-01 [PMID: 11378269] (Human)
• Bottcher MF, Jenmalm MC, Bjorksten B, Garofalo RP Chemoattractant factors in breast milk from allergic and nonallergic mothers. Pediatr. Res., 2000-05-01;47(5):592-7. 2000-05-01 [PMID: 10813582] (Human)
• Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. J. Neurochem., 2000-03-01;74(3):1017-25. 2000-03-01 [PMID: 10693932] (Human)
• Gauduin MC, Glickman RL, Ahmad S, Yilma T, Johnson RP Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and beta-chemokine production. Proc. Natl. Acad. Sci. U.S.A., 1999-11-23;96(24):14031-6. 1999-11-23 [PMID: 10570193] (Primate)
• Lauw FN, Dekkers PE, te Velde AA, Speelman P, Levi M, Kurimoto M, Hack CE, Van Deventer SJ, van der Poll T Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. J. Infect. Dis., 1999-03-01;179(3):646-52. 1999-03-01 [PMID: 9952371] (Primate - Pan troglodytes (Chimpanzee))
• Lehner T, —îÊëÖ“§, Wang Y, r¹oŽ&A½ýx, Cranage M, Ïï§Ù´âoÑ‘, Bergmeier LA, Mitchell E, Tao L, Hall G, Dennis M, Cook N, Brookes R, Klavinskis L, Jones I, Doyle C, Ward R Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. 1996-07-01;2(7):767-75. 1996-07-01 [PMID: 8673922] (Primate - Macaca mulatta (Rhesus Macaque))

FAQs for CCL3/MIP-1 alpha (DMA00). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: CCL3