Mouse CXCL2/MIP-2 Quantikine ELISA Kit, 2 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse CXCL2/MIP-2 Quantikine ELISA Kit, 2 Plate Summary

Background
The Quantikine Mouse MIP-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse MIP-2 levels in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse MIP-2 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse MIP-2 accurately. Results obtained using natural mouse MIP-2 ...showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse MIP-2.
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Specificity
Natural and recombinant mouse MIP-2
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Cxcl2

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using MM200.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CXCL2/MIP-2 Quantikine ELISA Kit, 2 Plate

  • chemokine (C-X-C motif) ligand 2
  • CINC-2a
  • CINC3
  • CINC-3
  • C-X-C Motif Chemokine 2
  • CXCL2
  • GRO beta
  • GRO2 oncogene
  • GRO2
  • GROB
  • Gro-beta
  • Growth-regulated protein beta
  • Macrophage inflammatory protein 2-alpha
  • melanoma growth stimulatory activity beta
  • MGSA beta
  • MGSA-b
  • MGSA-beta
  • MIP2
  • MIP-2
  • MIP2A
  • MIP-2a
  • MIP2-alpha
  • SCYB2

Background

CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CXCL2/GRO beta/MIP-2/CINC-3 (MM200)(154)

We have publications tested in 2 confirmed species: Mouse, Rat.


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Mouse
(150)
Rat
(1)
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Showing Publications 1 - 10 of 154. Show All 154 Publications.
Publications using MM200 Applications Species
SN Chang, DK Dey, ST Oh, WH Kong, KH Cho, EM Al-Olayan, BS Hwang, SC Kang, JG Park Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1&alpha-NF-&kappaB Crosstalk In Vitro and In Vivo International Journal of Molecular Sciences, 2020;21(23):. 2020 [PMID: 33291656] (Mouse) Mouse
MT Hoffman, SB Kemp, DJ Salas-Esca, Y Zhang, NG Steele, S The, D Long, S Benitz, W Yan, RF Margolskee, F Bednar, M Pasca di M, HJ Wen, HC Crawford The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice Cell Mol Gastroenterol Hepatol, 2020;0(0):. 2020 [PMID: 32882403] (Mouse) Mouse
WC Chen, NJ Chen, HP Chen, WK Yu, VY Su, H Chen, HH Wu, KY Yang Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis Int J Mol Sci, 2020;21(13):. 2020 [PMID: 32630825] (Mouse) Mouse
M Yoshikawa, T Iriyama, K Suzuki, S Sayama, T Tsuruga, K Kumasawa, T Nagamatsu, K Homma, I Naguro, Y Osuga, H Ichijo, T Fujii ASK1 promotes uterine inflammation leading to pathological preterm birth Sci Rep, 2020;10(1):1887. 2020 [PMID: 32024889] (Mouse) Mouse
JJ Yang, YC Huang, TH Chuang, DR Herr, MF Hsieh, CJ Huang, CM Huang Cysteine-Capped Hydrogels Incorporating Copper as Effective Antimicrobial Materials against Methicillin-Resistant Staphylococcus aureus Microorganisms, 2020;8(2):. 2020 [PMID: 31973160] (Mouse) Mouse
M Matsuda, K Doi, T Tsutsumi, M Inaba, J Hamaguchi, T Terada, R Kawata, K Kitatani, T Nabe Adoptive transfer of type 1 regulatory T cells suppressed the development of airway hyperresponsiveness in ovalbumin-induced airway inflammation model mice J. Pharmacol. Sci., 2019;141(4):139-145. 2019 [PMID: 31744690] (Mouse) Mouse
K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice Dis Model Mech, 2019;0(0):. 2019 [PMID: 31562139] (Mouse) Mouse
K Kojima, K Asai, H Kubo, A Sugitani, Y Kyomoto, A Okamoto, K Yamada, N Ijiri, T Watanabe, K Hirata, T Kawaguchi Isoflavone Aglycones Attenuate Cigarette Smoke-Induced Emphysema via Suppression of Neutrophilic Inflammation in a COPD Murine Model Nutrients, 2019;11(9):. 2019 [PMID: 31470503] (Mouse) Mouse
KJ Warren, JD Dickinson, AJ Nelson, TA Wyatt, DJ Romberger, JA Poole Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust Respir. Res., 2019;20(1):51. 2019 [PMID: 30845921] (Mouse) Mouse
N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells JCI Insight, 2019;0(0):. 2019 [PMID: 30720466] (Mouse) Mouse
Show All 154 Publications.

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Product General Protocols

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FAQs for CXCL2/GRO beta/MIP-2/CINC-3 (MM200). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP MM200
HRP MM200
HRP MM200

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Bioinformatics

Gene Symbol Cxcl2