CCL3/MIP-1 alpha Products

Description

Macrophage inflammatory protein-1 alpha (MIP-1 alpha) belongs to the intercrine beta (chemokine CC) family (1). MIP-1 alpha is involved in the acute inflammatory state, in the recruitment and activation of polymorphonuclear leukocytes and can inhibit infection of cells with human immunodeficiency virus type 1 (HIV-1) (2). MIP-1 alpha also acts as a potent growth, survival, and chemotactic factor in multiple melanoma cells. Two know isoforms of MIP-1 alpha can be found; LD78 alpha and LD78 beta (3). Depending on the isoform or its N-terminal processing, one or more of the CC chemokine receptors CCR1, CCR2, CCR3 and CCR5 can recognize MIP alpha, thus inhibiting HIV infection (4).

Bioinformatics

Entrez	6348 Human
Uniprot	P10147
Product By Gene ID	6348
Alternate Names	C-C motif chemokine 3 MIP1-(a) AI323804 CCL3 chemokine (C-C motif) ligand 3 G0S19-1 LD78a LD78alpha MIP1 alpha MIP-1 alpha MIP1A MIP-1alpha MIP1-alpha PAT 464.1 SCYA3 SIS-beta

Research Areas for CCL3/MIP-1 alpha

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytokine Research
Immunology
Innate Immunity
Signal Transduction