HSP60 Antibody Summary
A portion of amino acids 350-400 of human Hsp60 was used as the immunogen.
The amino acid sequence used as immunogen is 100% homologous in a broad range of species including human, dog, mouse, rat, bovine, chicken, chimp, monkey, and orangutan.
Protein G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Cross reacts with Bovine, Chicken, Chimpanzee, Dog, Human and New Word Monkey.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS containing 0.2% gelatin
0.05% Sodium Azide
Protein G purified
Alternate Names for HSP60 Antibody
- 60 kDa chaperonin
- Chaperonin 60
- heat shock 60kD protein 1 (chaperonin)
- heat shock 60kDa protein 1 (chaperonin)
- Heat shock protein 60
- heat shock protein 65
- Mitochondrial matrix protein P1,60 kDa heat shock protein, mitochondrial
- P60 lymphocyte protein
- short heat shock protein 60 Hsp60s1
- spastic paraplegia 13 (autosomal dominant)
HSP60, a 60KDa member of Chaperonin family, is a mitochondrial protein that participates in protein folding, transport and secretion. HSP60 is a multi-functional protein whose roles include accelerating the maturation of pro-caspase 3 during apoptosis, LPS-binding, acting as a ligand for innate immune system and also binding to the surface of innate immune cells and stimulating proinflammatory reactivity. It induces the expression of IL-12 and IL-15 and also induces release of TNF-alpha, NO and IL-6. Reports suggest interaction of Hsp60 with integrin molecules during metastasis. Mutations in Hsp60 gene cause autosomal recessive spastic paraplegia 13. Hsp60 has been found to be involved in development of auto-immune disorders such as Rheumatoid arthritis, insulin-dependent diabetes mellitus, systemic sclerosis and atherosclerosis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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FAQs for HSP60 Antibody (NB100-56469) (0)
Positive Control Lysate(s)
Additional HSP60 Products
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Bioinformatics Tool for HSP60 Antibody (NB100-56469)
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Blogs on HSP60.
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Customer Experience using HSP60 Antibody
I began using the HSP60 antibody (NB110-57063) in June of 2010 and it worked well. I do not like to buy antibodies that have not been tested in the species for which I will use them, so I picked this antibody because it had already been tested in rat... Read full blog post.
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