The immunogen recognized by this antibody maps to a region between residue 1985 and 2035 of human host cell factor C1 (VP16-accessory protein) using the numbering given in entry NP_005325.2 (GeneID 3054).
Rat (100%), Bovine (100%), Bat (100%), Equine (100%), Rabbit (100%), Primate (100%), Canine (100%)
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Reactivity with mouse reported by a customer review. Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Duckbill platypus, Tasmanian devil, Dusky titi monkey, Olive baboon, African elephant, Golden hamster and Greater horseshoe bat.
Alternate Names for Host Cell Factor 1/HCFC1 Antibody
HCF-1VP16 accessory protein
host cell factor C1 (VP16-accessory protein)
VCAFhost cell factor 1
This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.