Host Cell Factor 1/HCFC1 Products

Description

HCFC1 is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Bioinformatics

Entrez	3054 Human
Uniprot	AAH63435.1 Human NP_005325.2 Human P51610 Human
Product By Gene ID	3054
Alternate Names	CFFC1 factor HCF HCF1HFC1 HCF-1VP16 accessory protein host cell factor C1 (VP16-accessory protein) MGC70925 VCAFhost cell factor 1