Hormone-sensitive Lipase/HSL Antibody [Janelia Fluor® 646]

• Reactivity: Hu, Mu, Rt, Po, Bv
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 646

Hormone-sensitive Lipase/HSL Antibody [Janelia Fluor® 646] Summary

• Immunogen: Antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Lipe. The immunogen is located within amino acids 920 - 970 of Lipe. Amino Acid Squence: FPEGFHPRRSSQGA
• Specificity: Multiple isoforms of Lipe are known to exist.
• Predicted Species: Porcine (100%), Bovine (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LIPE
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Hormone-sensitive Lipase/HSL Antibody [Janelia Fluor® 646]

• hormone-sensitive lipase testicular isoform
• Hormonesensitive Lipase
• Hormone-sensitive Lipase
• HSL
• HSLEC 3.1.1.79
• LHS
• lipase, hormone-sensitive
• LIPE

Background

Hormone-sensitive lipase (HSL) is an intracellular neutral lipase found in a variety of tissues, but primarily in adipose and steroidogenic tissues. It hydrolyzes triglycerides into free fatty acids and cholesteryl esters into free cholesterol for steroid hormone synthesis.

HSL is the major enzyme responsible for the mobilization of free fatty acids from adopise tissue, and HSL antibodies are useful tools for lipid and metabolism research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LIPE