HLA D Antibody (7.5.10.1)

• Reactivity: Hu, Ca
• Applications: ICC/IF
• Clone: 7.5.10.1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

HLA D Antibody (7.5.10.1) Summary

• Immunogen: The antibody reacts with a monomorphic determinant on MHC class II, HLA-D region molecules.
• Specificity: The antibody detects the molecules of the HLA-DR, DP and DQ loci. It inhibits the mixed lymphocyte culture. It also reacts with MHC class II molecules of various animals and is a useful tool for studies with dogs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: HLA-DQA1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:5
• Application Notes: The antibody is useful for the identification of HLA-D positive molecules using either microcytotoxicity testing or immunofluorescence/immunoperoxidase procedures. Furthermore, it was found useful for studies on functional aspects of MHC class II molecules. For use in regular immunofluorescence and microcytotoxicity methods, dilution of 1:5, preferably in PBS plus 1% BSA and 0.01% sodium azide is advised. See for advised methods instructions A and B.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS, 0.1% BSA
• Preservative: 0.01% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for HLA D Antibody (7.5.10.1)

• CD
• CELIAC1DQ alpha 1 chain
• DC-1 alpha chain
• DQ-A1
• FLJ27088
• FLJ27328
• GSE
• HLA class II histocompatibility antigen, DQ(W3) alpha chain
• HLA-DCA
• HLA-DQA
• leucocyte antigen DQA1
• leukocyte antigen alpha chain
• major histocompatibility complex, class II, DQ alpha 1
• MGC149527
• MHC class II antigen
• MHC class II DQA1
• MHC class II HLA-D alpha glycoprotein
• MHC class II HLA-DQ-alpha-1
• MHC class II surface glycoprotein
• MHC HLA-DQ alpha

Background

The antibody is useful for the identification of HLA-D positive molecules using either microcytotoxicity testing or immunofluorescence/immunoperoxidase procedures. Furthermore, it was found useful for studies on functional aspects of MHC class II molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HLA-DQA1