HADH Antibody

Product Discontinued

HADH Antibody Summary

• Immunogen: Antibody target: HADH/HCDH
  Synthetic peptide surrounding amino acid 305 of rat HADH/HCDH
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HADH
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: The antibody can be used for Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. Blocking peptide is available separately.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2), 0.5% BSA, 5mM EDTA and 30% Glycerol
• Preservative: 0.01% Thimerosal
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for HADH Antibody

• EC 1.1.1
• EC 1.1.1.35
• HADH1
• HADHSChydroxyacyl-Coenzyme A dehydrogenase
• HCDH
• hydroxyacyl-CoA dehydrogenase
• L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain
• Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase
• MGC8392
• mitochondrial
• MSCHAD
• SCHADHHF4

Background

L-3-hydroxyacyl-CoA dehydrogenase (HADH/HCDH) is a mitochondrial matrix protein expressed in pancreas, liver, heart, kidney and skeletal muscle. L-3-hydroxyacyl-CoA dehydrogenase catalyzes the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene can lead to HADH (3-a-hydroxyacyl-CoA dehydrogenase) deficiency and familial hyperinsulinemic hypoglycemia 4 (HHF4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HADH
• Uniprot:
  • Q9WVK7(Rat)