GSAP Antibody

Images

 
Western Blot: GSAP Antibody [NBP1-78376] - Analysis of GSAP in HepG2 cell lysate.
Simple Western: GSAP Antibody [NBP1-78376] - Simple Western lane view shows a specific band for GSAP in 0.5 mg/ml of HepG2 lysate. This experiment was performed under reducing conditions using the 12-230 kDa ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Simple Western
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.11 mg/ml

GSAP Antibody Summary

Immunogen
A synthetic peptide made to an internal portion of the human GSAP protein (between residues 100-150) [UniProt A4D1B5]
Localization
Golgi apparatus, trans-Golgi network.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PION
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Simple Western 1:100
Application Notes
This GSAP antibody is useful for Western Blot where a band is observed ~65 kDa representing Isoform 2/3 of GSAP.

In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
Control
HepG2 Lysate (NBP1-42569)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 30% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1.11 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GSAP Antibody

  • Gamma-secretase-activating protein
  • GSAP
  • pigeon homolog (Drosophila)
  • PION
  • tcag7.1314

Background

Gamma secretase activating protein (GSAP) is implicated in Alzheimer's disease, through instigating plaque formation of amyloid beta. Immunohistochemistry to identify GSAP in brain can demonstrate its abundance in certain regions of damage, and is usually morphologically changed throughout the progression of Alzheimer's disease. GSAP can be used as a qualitative biomarker of Alzheimer's disease progression, and is regularly considered one of the best targets of therapies to diminish the effects of Alzheimer's disease in affected individuals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

View specific protocols for GSAP Antibody (NBP1-78376): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for GSAP Antibody (NBP1-78376) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-78376AF405
Alexa Fluor 488 Labeled NBP1-78376AF488
Alexa Fluor 647 Labeled NBP1-78376AF647
Alexa Fluor 700 Labeled NBP1-78376AF700
Biotin Labeled NBP1-78376B
DyLight 405 Labeled NBP1-78376V
DyLight 488 Labeled NBP1-78376G
DyLight 550 Labeled NBP1-78376R
DyLight 650 Labeled NBP1-78376C
HRP Labeled NBP1-78376H

Additional Array Products

Array NBP1-78376

Bioinformatics Tool for GSAP Antibody (NBP1-78376)

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Calculators

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Bioinformatics

Gene Symbol PION
Entrez
Uniprot