Granzyme B Antibody (CLB-GB11)


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Product Details

Reactivity Hu, PmSpecies Glossary
Applications Flow
1 mg/ml

Granzyme B Antibody (CLB-GB11) Summary

Human NK cell line YT-INDY-derived granzyme B
The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed in activated Tc cells and NK cells.
Protein A purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
TBS, pH 8.0
15mM Sodium Azide
1 mg/ml
Protein A purified


  • Flow Cytometry 1:10-1:1000

Alternate Names for Granzyme B Antibody (CLB-GB11)

  • CSPB
  • CTLA-1
  • CTSGL1
  • Fragmentin-2
  • Granzyme-2
  • GRB
  • GrzB
  • GZMB
  • HLP
  • SECT


Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover, granzyme B was reported to cleave directly alpha-tubulin, leading to perturbation of microtubule networks during the induced cell death.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP1-50071AF405
Alexa Fluor (R) 488 Labeled NBP1-50071AF488
Alexa Fluor (R) 647 Labeled NBP1-50071AF647
Alexa Fluor (R) 700 Labeled NBP1-50071AF700
Allophycocyanin Labeled NBP1-50071APC
DyLight 350 Labeled NBP1-50071UV
DyLight 405 Labeled NBP1-50071V
DyLight 405LS Labeled NBP1-50071V3
DyLight 488 Labeled NBP1-50071G
DyLight 680 Labeled NBP1-50071FR
DyLight 755 Labeled NBP1-50071IR
PE Labeled NBP1-50071PE
PerCP Labeled NBP1-50071PCP

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Blogs on Granzyme B.

Caspase 3, the executioner of apoptosis
Caspase-3 enzyme is a member of the family of endoproteases which regulate inflammation and apoptosis signaling networks. Caspase-3 is known as an executioner caspase in apoptosis because of its role in coordinating the destruction of cellular stru...  Read full blog post.

Caspase 9: The Suicidal Cell Whisperer
Cell death via apoptosis is a key cellular function triggered by the cell death receptor family and their ligands which signal through downstream adaptor molecules and the caspase protease family. Among the subclass of initiator caspases that include...  Read full blog post.

Caspase 7: The Cell's Suicide Switch
Caspase 7 (also known as CASP7, Mch3, ICE-LAP3, CMH-1) is a member of caspase family of cysteine proteases. It is an apoptosis-related cystein peptidase encoded by the CASP7 gene in humans. CASP7 homologous sequences have been identified in nearly all...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol GZMB

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