Granulin Antibody Pair [HRP]

ELISA: Granulin Antibody Pair [HRP] [NBP3-11653] - Sample standard curve

• Reactivity: Mu
• Applications: ELISA
• Conjugate: HRP
• Standard Curve Range: 39.06-2500 pg/ml (example only; lot dependent)
• Sensitivity: 39.06 pg/ml (example only; lot dependent)

Granulin Antibody Pair [HRP] Summary

• Description: This Granulin Mouse Granulin Antibody Pair [HRP] is a solid phase sandwich ELISA for quantitative determination of Mouse Granulin.
• Additional Information: Recombinant Monoclonal Antibody
• Specificity: This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Mouse Granulin.
• Source: HEK293
• Standard Curve Range: 39.06-2500 pg/ml (example only; lot dependent)
• Sensitivity: 39.06 pg/ml (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Sample Volume: 100 ul
• Gene: GRN

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Granulin Antibody Pair [HRP]

• acrogranin
• GEP
• GP88
• granulin
• granulin-epithelin
• granulins
• PC cell-derived growth factor
• PCDGF
• PEPI
• PGRN
• proepithelin
• progranulin

Background

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: GRN