Granulin Products

Antibodies
Granulin Antibody
Granulin Antibody
NBP1-32076
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Granulin Antibody
Granulin Antibody
NBP1-87324
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Granulin Antibody (CL5695)
Granulin Antibody (CL5695)
NBP2-61425
Species: Hu
Applications: WB, IHC-P
Host: Mouse Monoclonal
Antibody Pairs
Granulin Antibody Pair
Granulin Antibody Pair
H00002896-AP41
Species: Hu
Applications: S-ELISA
Lysates
Granulin Overexpression Lysat ...
Granulin Overexpression Lysate (De...
H00002896-T01
Species: Hu
Applications: WB
Granulin Overexpression Lysat ...
Granulin Overexpression Lysate (Na...
NBL1-11353
Applications: WB
Proteins
Recombinant Human Granulin Pr ...
Recombinant Human Granulin Protein
H00002896-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human Granulin Pr ...
Recombinant Human Granulin Protein
NBP1-99540
Species: Hu
Applications: PAGE, HPLC
Recombinant Human Granulin Pr ...
Recombinant Human Granulin Protein
H00002896-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Granulin RNAi
Granulin RNAi
H00002896-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 2896
Alternate Names
  • acrogranin
  • Proepithelin
  • GP88
  • progranulin
  • GEP
  • proepithelin
  • PEPI
  • PC cell-derived growth factor
  • PGRN
  • granulins
  • PCDGF
  • granulin-epithelin
  • granulin

Research Areas for Granulin

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

Bioinformatics Tool for Granulin

Discover related pathways, diseases and genes to Granulin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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