GRAIL/RNF128 Antibody

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Immunohistochemistry-Paraffin: GRAIL/RNF128 Antibody [NBP2-97643] - Immunochemical staining of human GRAIL/RNF128 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

GRAIL/RNF128 Antibody Summary

Description
This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Immunogen
Produced in rabbits immunized with E. coli-derived Human GRAIL/RNF128 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RNF128
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:50-1:200

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0)
Preservative
0.03% Proclin 300
Purity
Antigen and protein A Affinity-purified

Alternate Names for GRAIL/RNF128 Antibody

  • EC 6.3.2
  • EC 6.3.2.-
  • FLJ23516
  • Gene related to anergy in lymphocytes protein
  • GRAIL
  • ring finger protein 128GRAILE3 ubiquitin-protein ligase RNF128
  • RNF128

Background

The protein encoded by the RNF128 gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RNF128