Species: Hu, Mu, Rt, Ca, Eq, Pm, Bv, Pm, Pm, Pm-Or
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Description
The protein encoded by the RNF128 gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
79589 |
| Alternate Names |
- EC 6.3.2
- EC 6.3.2.-
- FLJ23516
- Gene related to anergy in lymphocytes protein
- ring finger protein 128GRAILE3 ubiquitin-protein ligase RNF128
|
