Biological Strategies: Western Blot: GRAIL/RNF128 Antibody [NBP2-24610] - Bone marrow progenitors were isolated from C57BL/6 mice and incubated with 20ng/ml GM-CSF. (a) Cells were collected at days 0-9. A portion ...read more
Immunohistochemistry-Paraffin: GRAIL/RNF128 Antibody [NBP2-24610] - Staining of normal human brain using control (rabbit Ig) at 5 ug/ml.
Western Blot: GRAIL/RNF128 Antibody [NBP2-24610] - Analysis of human GRAIL in human spleen lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse spleen and 4) rat spleen using NBP2-24610 at 1 ug/ml.
The amino acid sequence used as immunogen is 100% homologous in chimpanzee, monkey and orangutan, 94% homologous in cow, 88% homologous in cat and 83% homologous in opossum, rat and mouse.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.05% Sodium Azide
Protein A purified
Alternate Names for GRAIL/RNF128 Antibody
Gene related to anergy in lymphocytes protein
ring finger protein 128GRAILE3 ubiquitin-protein ligase RNF128
The protein encoded by the RNF128 gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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