Gr-1/Ly-6G Antibody (AP-MAB0866) - Azide and BSA Free

• Reactivity: Mu
• Applications: Flow, Func, IHC, IP, CyTOF-ready
• Clone: AP-MAB0866
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1.0 mg/ml

Gr-1/Ly-6G Antibody (AP-MAB0866) - Azide and BSA Free Summary

• Description: Novus Biologicals Rat Gr-1/Ly-6G Antibody (AP-MAB0866) - Azide and BSA Free (NBP1-06691) is a monoclonal antibody validated for use in IHC, Flow and IP. Anti-Gr-1/Ly-6G Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Mouse spontaneous T lymphoma line TK1
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: Ly6g
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • In vivo assay
• Application Notes: In vivo depletion of PMN and Myeloid suppressor cells. Endotoxin level: Extremely low level of LPS (< 0.002EU/ug IgG) This antibody may also be useful in IHC-frozen. This antibody is CyTOF ready.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for Gr-1/Ly-6G Antibody (AP-MAB0866) - Azide and BSA Free

• Gr1
• Gr-1
• Ly-6C
• Ly6G
• Ly-6G
• ly-6G.1
• Ly-6G/Ly-6C (Gr-1)
• lymphocyte antigen 6 complex, locus G
• lymphocyte antigen 6G

Background

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Gr-1+ cells have recently been implicated in the development of antitumor responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Gr-1/Ly-6G Antibody (NBP1-06691)(1)

Publication using NBP1-06691

• Chadwick C, De Jesus M, Ginty F et Al. Pathobiology of Candida auris infection analyzed by multiplexed imaging and single cell analysis PLoS One 2024-01-17 [PMID: 38232081]

Bioinformatics

• Gene Symbol: Ly6g
• Entrez:
  • 546644(Mouse)