GPER/GPR30 Antibody

Images

 
Immunohistochemistry-Paraffin: GPER/GPR30 Antibody [NLS4268] - Analysis of anti-GPR30 antibody with human skeletal muscle at dilution 5 - 7.5 ug/ml.
Immunohistochemistry-Paraffin: GPER/GPR30 Antibody [NLS4268] - Analysis of anti-GPR30 antibody with human, spleen.

Product Details

Summary
Reactivity Hu, Mk, PmSpecies Glossary
Applications ELISA, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

GPER/GPR30 Antibody Summary

Immunogen
Synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR30.
Localization
Endoplasmic reticulum - multi-pass membrane protein.
Specificity
Human GPR30. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (93%), Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPER
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry-Paraffin 1:10 - 1:500
Publications
Read Publication using NLS4268.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (93%), Elephant (93%), Mouse (87%), Rat (87%), Hamster (87%), Panda (87%), Equine (87%), Opossum (87%), Platypus (87%), Canine (80%), Bovine (80%), Turkey (80%), Zebra finch (80%), Chicken (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GPER/GPR30 Antibody

  • CEPR
  • CEPRG-protein coupled receptor 30
  • Chemoattractant receptor-like 2
  • chemokine receptor-like 2
  • CMKRL2
  • CMKRL2MGC99678
  • constitutively expressed peptide-like receptor
  • DRY12
  • DRY12IL8-related receptor DRY12
  • FEG-1
  • FEG-1mER
  • Flow-induced endothelial G-protein coupled receptor 1
  • G protein-coupled estrogen receptor 1
  • G protein-coupled receptor 30
  • GPCR-BR
  • GPER
  • GPR30
  • GPR30GPCR-Br
  • G-protein coupled estrogen receptor 1
  • heptahelix receptor
  • LERGU
  • LERGU2
  • leucine rich protein in GPR30 3'UTR
  • LyGPR
  • Lymphocyte-derived G-protein coupled receptor
  • Membrane estrogen receptor

Background

GPR30 is a transmembrane intracellular estrogen receptor (Revankar et al. 2005). Progestin inhibits growth in breast cancer cells through GPR30. GPR30 has been reported in brain, breast carcinoma, blood, bone marrow, CNS, heart, liver, lung, lymph node, placenta, and spleen. ESTs have been isolated from B-cell/lung/testis, brain, ganglion, heart/melanocyte/uterus, kidney, tonsil, liver/spleen, placenta, and prostate libraries. Ligands: Estrogen (Revankar et al. 2005). Caution: Rat GPR30 is also known as GPR41 and HIA-R

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GPER
Entrez
Uniprot