GNPTG Antibody [Allophycocyanin]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Allophycocyanin

GNPTG Antibody [Allophycocyanin] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human GNPTG fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GNPTG
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Alternate Names for GNPTG Antibody [Allophycocyanin]

• C16orf27
• c316G12.3
• CAB56184
• GlcNAc-1-phosphotransferase subunit gamma
• GNPTAGchromosome 16 open reading frame 27
• LP2537
• N-acetylglucosamine-1-phosphate transferase, gamma subunit
• N-acetylglucosamine-1-phosphotransferase subunit gamma
• N-acetylglucosamine-1-phosphotransferase, gamma subunit
• RJD9
• UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma

Background

GNPTG, also known as N-acetylglucosamine-1-phosphotransferase subunit gamma, is a 305 amino acid that is 34 kDa,; hexamer composed of two alpha, two beta and two gamma subunits, widely expressed; catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker, essential for targeting of lysosomal hydrolases to the lysosome. Studies are being performed on the relationship of this protein to mucolipidosis iii gamma, mucolipidosis, mucolipidosis iiic, mucolipidosis ii, dysostosis, short stature, autosomal recessive disease, scoliosis, parkinson's disease, ovarian carcinoma, and retinitis. GNPTG protein involvement has been observed with relation to UPF1 and GNPTAB proteins in the lysosome pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNPTG