Glutamate Receptor 3 Antibody (1059821) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 1059821
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Glutamate Receptor 3 Antibody (1059821) [Alexa Fluor® 647] Summary

• Immunogen: Synthetic Peptide
  Accession # P42263
• Specificity: Detects human GluR3 in direct ELISA.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Glutamate Receptor 3 Antibody (1059821) [Alexa Fluor® 647]

• AMPA 3
• AMPA3
• AMPA-selective glutamate receptor 3
• GluA3
• GluR3
• GluR-3
• GLURC
• GLUR-C
• GLUR-K3
• glutamate receptor C
• glutamate receptor subunit 3
• glutamate receptor, ionotrophic, AMPA 3
• GRIA3

Background

GluR3 is a receptor for glutamate. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiological processes. This gene belongs to a family of AMPA receptors.  GluR3 is a gene product of the GRIA3 gene and its pre-mRNA is subject to RNA editing. In humans, 80-90% of GRIA3 transcripts are edited. This allows sustained response to rapid stimuli. There is a tentative link between defective GRIA3 variants and a highly elevated risk of schizophrenia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.