A synthetic peptide from extracellular domain of human GluR2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
GRIA2
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
The optimal dilution should be determined by the end user. Use in immunoprecipitation reported in scientific literature (PMID: 27461448). Use in ICC/IF, and IHC-FR reported in scientific literature (PMID: 30150703).
Publications
Read Publications using NBP1-46490 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Lyophilized from whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the sample size is provided in reconstituted format.
Alternate Names for GluR2 Antibody
AMPA 2
AMPA2
GluA2
GluR2
GLURB
GluR-K2
glutamate receptor, ionotropic, AMPA 2
GRIA2
HBGR2
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The ionotropic glutamate receptors are multimeric assemblies of four or five subunits, and are subdivided into three groups (AMPA, NMDA and Kainate receptors) based on their pharmacology structural similarities. The ionotropic receptors are ligand gated ion channels, i.e. on binding glutamate that has been released from a companion cell, charged ions such as Na+ and Ca2+ pass through a channel in the centre of the receptor complex. This flow of ions results in a depolarisation of the plasma membrane and the generation of an electrical current that is propagated down the processes (dendrites and axons) of the neuron to the next in line.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
=
÷
Review this Product
Be the first to review our GluR2 Antibody and receive a gift card or discount.